Modulight Spotlights: LASER-SHARP RESEARCH – February 2024

Modulight Spotlights: LASER-SHARP RESEARCH – February 2024

Photoactivated chemotherapy (PACT) is a novel anticancer therapy where cytotoxic drug is attached into a photocage, which is cleaved by light to release the drug at the tumor site. A new study led by Prof. Sylvestre Bonnet’s group at Leiden University, demonstrated a significantly improved agent for photoactivated chemotherapy. ML6600 laser was used to study the drug release from the photocage, comparing efficacy between red and green light. It was shown that the agent could be effectively released by red light, which can penetrate deeper into the tumor tissue and is also supported by many clinically used lasers, unlike the typical green-light activated PACT agents. Impressively, therapy resulted in significant tumor mass reduction and was also effective in hypoxic (low oxygen) conditions, commonly observed in many solid tumors.


Modulight is very happy to be supporting this research. We would like to deliver our warmest congratulations to the research team!


#Laser-Sharp Research  #PACT  #photoactivatedchemo #hypoxia  #oncology


Modulight products used:

ML6600 – High-power laser system with multi-wavelength support

Read more:

In-vitro and in-vivo illumination »

About Modulight’s LASER-SHARP RESEARCH concept:

Laser-Sharp Research is a concept where our scientific board highlights cutting-edge scientific research articles from our customers. Important selection criteria are that Modulight and laser product are mentioned in the publication, the impact and relevance of the results, clinical translatability, as well as scientific quality of the journal. The nominated research groups will be rewarded to encourage the great work done.

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Do you have questions or comments related to this LASER-SHARP RESEARCH nomination? Maybe your group has done significant research  that your would like us to spotlight?  Or would you like to request literature? Please drop us a line!

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