Tag Archives: ML6600

ML6600 Expands with VECSEL-Based Variants for Flow Cytometry

January 17, 2025 by Modulight Content
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Advancing Flow Cytometry Precision with VECSEL Laser Cores Advancing Flow Cytometry Precision with VECSEL Laser Cores  Modulight expands its ML6600 product family with new variants designed to meet the rigorous demands of flow cytometry applications. Featuring Modulight’s OP-VECSEL (Optically-Pumped Vertical-External-Cavity Surface-Emitting Laser)  core technology, these latest ML6600 variants offer unprecedented performance and reliability for biomedical research and diagnostics.  Building on the success of the ML6600 platform, the new variants provide ultra-low-noise continuous-wave (CW) emission with diffraction-limited beam quality and efficient harmonic generation for optical power scaling up to one Watt level. The platform Continue reading →

ML6640: A 4-Wavelength Laser Engine for Flow Cytometry

January 17, 2025 by Modulight Content
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Modulight Introduces ML6640: Redefining Flow Cytometry PerformanceModulight Introduces ML6640: Redefining Flow Cytometry Performance Modulight is proud to announce the ML6640, the latest addition to its ML6600 product family, designed for flow cytometry and cell sorting applications. This advanced laser engine incorporates four precisely selected wavelengths—405 nm, 488 nm, 561 nm, and 638 nm (for other wavelengths contact factory)—optimized for fluorochrome excitation, including PE (Phycoerythrin)-based dyes critical for multi-parameter analysis. The ML6640 introduces an innovative active beam alignment system powered by artificial intelligence (AI). This cutting-edge technology dynamically monitors and adjusts laser Continue reading →

Introducing VECSEL Technology to the Modulight ML6600 Platform for Quantum Applications

January 2, 2025 by Modulight Content
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Modulight ML6600 Expands to Meet Quantum Application NeedsModulight ML6600 Expands to Meet Quantum Application Needs Modulight is proud to announce new additions to its ML6600 product platform, tailored specifically for quantum applications. Building on the proven ML6600 platform, these latest variants integrate Modulight’s innovative VECSEL (Vertical-External-Cavity Surface-Emitting Laser) core technology, redefining precision and flexibility for quantum computing and sensing. Designed to address the stringent requirements of atomic, molecular, and optical (AMO) physics, the ML6600 platform for quantum applications features ultra-low-noise continuous-wave (CW) single-frequency emission with sub-100 kHz free-running linewidth and efficient intracavity Continue reading →

ML6600-based Laser Solutions for Microscopy

January 2, 2025 by Modulight Content
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Modulight Introduces Laser Engines for MicroscopyModulight Introduces Laser Engines for Microscopy Modulight proudly announces new variants of its ML6600 platform, designed specifically for the demanding requirements of microscopy illumination, such as super-resolution microscopy. These advanced solutions support both single-wavelength and multi-wavelength configurations, tailored to meet diverse customer needs in imaging applications. ML6600 platform provides all key wavelengths for microscopy—for example 405 nm, 488 nm, 561 nm, and 638 nm (other wavelengths available upon request)—delivered via fiber-coupled or free-space beam options. Light is delivered through exceptionally small single fiber cores, starting Continue reading →

Modulight 632.8 nm DBR laser: A Superior Alternative to Traditional HeNe lasers

January 2, 2025 by Modulight Content
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Redefining Laser Technology with Compact and Reliable Alternatives to HeNe LasersRedefining Laser Technology with Compact and Reliable Alternatives to HeNe Lasers Modulight announces the launch of its 632.8 nm Distributed Bragg Reflector (DBR) semiconductor laser, designed to replace traditional HeNe lasers across a wide range of applications. Leveraging Modulight’s in-house #TailoredLaser capabilities, the 632.8 nm DBR laser offers significant advantages over HeNe lasers, including reduced power consumption and a very compact, robust design that eliminates the need for fragile gas tubes. The 632.8 nm DBR laser features a high power output of up to 25 Continue reading →

1762 nm Fiber Laser on the ML6600 Platform for Barium Ion Manipulation

January 2, 2025 by Modulight Content
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Delivering Unmatched Precision and Stability for Quantum ApplicationsDelivering Unmatched Precision and Stability for Quantum Applications Modulight’s ML6600 platform, known for supporting a wide range of laser technologies including fiber lasers, now features a new variant: the 1762 nm fiber laser, designed for the most stringent quantum applications. This advanced laser is specifically tailored for barium clock transition, addressing the demanding needs of quantum information processing, atomic clock development, and cutting-edge scientific research. Building on the low-noise capabilities of the ML6600 platform, the 1762 nm fiber laser combines the inherent stability of fiber Continue reading →

Modulight Spotlights: LASER-SHARP RESEARCH – November 2024

November 19, 2024 by Modulight Content
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 Modulight Spotlights: LASER-SHARP RESEARCH – November 2024 The lungs are common site of cancer metastasis, with isolated pulmonary metastases most often affecting patients with colorectal cancer and sarcomas. Surgical metastasectomy is the standard treatment, however, only 1 in 10 patients qualify for surgical resection thus the management remains a significant clinical challenge. To tackle this challenge, K. Ramadan et al. studied photodynamic therapy in an isolated lung perfusion model where the blood is replaced with acellular perfusate, allowing greater light penetration. The feasibility and safety Continue reading →

Self-Assembled Verteporfin Nanoparticles for Photodynamic and Light-Independent Therapy in Glioblastoma

September 28, 2024 by Modulight Content
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Published in: Advanced NanoBioMed Research Authors: John A. Quinlan, Kaylin Baumiller, Anandita Gaur, Wen-An Chiou, Robert W. Robey, Michael M. Gottesman, Huang-Chiao Huang  Published in: Advanced NanoBioMed Research Authors: John A. Quinlan, Kaylin Baumiller, Anandita Gaur, Wen-An Chiou, Robert W. Robey, Michael M. Gottesman, Huang-Chiao Huang A nanosuspension of verteporfin, termed NanoVP, that requires no carriers is developed, permitting delivery of VP alone in an aqueous solution. NanoVP is produced by solvent–antisolvent precipitation, with dimethyl sulfoxide as the preferable solvent. The paper describes the characterization of NanoVP, including bioavailability and anticancer capacity in glioblastoma with ML6600 laser irradiation, as well as potontial of NanoVP for light-independent therapy.   Read Continue reading →

Modulight Spotlights: LASER-SHARP RESEARCH – June 2024

June 12, 2024 by Modulight Content
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 Modulight Spotlights: LASER-SHARP RESEARCH – June 2024 A promising new therapy against viruses was developed at University of Manitoba and Theralase Technologies. Infectious agents are a global problem, causing millions of deaths every year. The study evaluated antiviral effectiveness of a cancer drug (Ruvidar), which is currently in clinical development for bladder cancer. When this drug was activated with green laser using Modulight’s ML6600, it resulted in a rapid elimination of many different human viruses. Impressively, it was >99% effective at low doses in inactivating human coronavirus, influenza Continue reading →

Modulight Spotlights: LASER-SHARP RESEARCH – May 2024

May 23, 2024 by Modulight Content
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 Modulight Spotlights: LASER-SHARP RESEARCH – May 2024 A new publication by Professor Bryan Spring and his team at Northeastern University has shown promising results for improved photoimmunotherapy protocols using patient-derived ovarian cancer cells. Using Modulight’s ML6000-series laser as part of the new protocol, they successfully minimized non-specific damage to cells that was caused by a small fraction of non-covalently bound (free) photosensitive drug, which is typically cleared in vivo by lymph and blood flow. They also showed the importance of using more biologically relevant cancer Continue reading →