Tag: oncology

Red-Light Activation of a Microtubule Polymerization Inhibitor via Amide Functionalization of the Ruthenium Photocage

Scientific papers / Modulight Content / hypoxia, in vitro, in vivo, ML6600, oncology, PACT, photoactivated chemotherapy

Published in: Angew Chem Int Ed Authors: Ludovic Bretin, Yurii Husiev, Vadde Ramu, Liyan Zhang, Matthijs Hakkennes, Selda Abyar, Andrew C.

Red-Light Activation of a Microtubule Polymerization Inhibitor via Amide Functionalization of the Ruthenium Photocage Read More »

Transient fluid flow improves photoimmunoconjugate delivery and photoimmunotherapy efficacy

Scientific papers / Modulight Content / 690 nm, benzoporphyrin, cetuximab, drug delivery, in vitro, liposomes, ML6600, oncology, ovarian cancer, PDT, peritoneal cavity, photoimmunoconjugates, Photoimmunotherapy, photosensitizer

Published in: iScience Authors: Aaron J. Sorrin, Keri Zhou, Katherine May, Cindy Liu, Kathryn McNaughton, Idrisa Rahman, Barry J. Liang,

Transient fluid flow improves photoimmunoconjugate delivery and photoimmunotherapy efficacy Read More »

Immune checkpoint inhibition combined with targeted therapy using a novel virus‑like drug conjugate induces complete responses in a murine model of local and distant tumors

Scientific papers / Modulight Content / 690 nm, AU-011, immune checkpoints, in vitro, in vivo, ML6600, MLAKIT, oncology, Photoimmunotherapy, targeted therapy, virus-like conjugates

Published in: Cancer Immunology, Immunotherapy Authors: Ruben V. Huis in ‘t Veld, Sen Ma, Rhonda C. Kines, Anneli Savinainen, Cadmus

Immune checkpoint inhibition combined with targeted therapy using a novel virus‑like drug conjugate induces complete responses in a murine model of local and distant tumors Read More »

Novel ophthalmic PDT laser platform to target oncology and various other retinal indications

Scientific papers / Modulight Content / age-related macular degeneration, AMD, BIOS, CSC, CSR, drug delivery, ML6710i, Modulight authors, Modulight Cloud, nAMD, oncology, ophthalmology, PCV, PDT, Retina, SLA, slit lamp adapter, SPIE BIOS 2023

Presented in: SPIE BIOS 2023 Authors: Laura Vesala, Eero Koivumäki, Jukka-Pekka Alanko, Timo Tanila, Ivan Baldin, Zoe Ylöniemi, Petteri Uusimaa,

Novel ophthalmic PDT laser platform to target oncology and various other retinal indications Read More »

Optimization of light delivery for non-muscle invasive bladder cancer PDT

Scientific papers / Modulight Content / BIOS, bladder cancer, drug delivery, light delivery, ML7710, Modulight authors, NMIBC, oncology, PDT, SPIE BIOS 2023

Presented in: SPIE BIOS 2023 Authors: Elias Kokko, Robert Perttilä, Zoe Ylöniemi, Visa Kaivosoja, Jukka-Pekka Alanko, Petteri Uusimaa, Modulight Corp.

Optimization of light delivery for non-muscle invasive bladder cancer PDT Read More »

Modulight Spotlights: LASER-SHARP RESEARCH – December 2022

Laser-sharp Research / Modulight Content / checkpointinhibitors, in vitro, in vivo, IRDye700, LaserSharpResearch, ML7710, oncology, Photoimmunotherapy

Modulight Spotlights: LASER-SHARP RESEARCH – December 2022 Read More »

Fluorescence imaging & endoscopy for tumor visualization and diagnostics

Application Note / Modulight Content / 5-ALA, bladder cancer, bronchoscopy, cystoscope, cystoscopy, endoscope, endoscopy, fluorescence, gastroscopy, ICG, imaging, indocyanine green, Lung cancer, ML7710, NIR endoscopy, oncology, RGB

Several fluorescent agents have been approved for fluorescence based diagnosis & intraoperative imaging: Dye generic name Countries Excitation Detection Indications

Fluorescence imaging & endoscopy for tumor visualization and diagnostics Read More »

Light-activated drug release using an automated well plate illuminator

Scientific papers / Modulight Content / biomedical, BIOS, cloud-connected, illumination system, indocyanine green, light activation, liposomes, ML8500, oncology, well plate

Presented in: SPIE BIOS 2022 Authors: Laura Vesala, Robert Perttilä, Elias Kokko, Lasse Orsila, Modulight Corporation (Finland), Tampere Univ. Hospital

Light-activated drug release using an automated well plate illuminator Read More »

Theranostic laser system for multi-function drug activation and monitoring

Scientific papers / Modulight Content / AI, BIOS, cloud-connected, laser platform, medical laser, oncology

Presented in: SPIE BIOS 2022 Authors: Robert Perttilä, Visa Kaivosoja, Elias Kokko, Zoe Ylöniemi, Lasse Orsila, Modulight Corporation (Finland), Tampere

Theranostic laser system for multi-function drug activation and monitoring Read More »