hypoxia

Modulight Spotlights: LASER-SHARP RESEARCH – October 2024

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Modulight Spotlights: LASER-SHARP RESEARCH – October 2024 This month, we are highlighting new findings published in RSC Materials Advances by Olga Lem, Roosa Kekki and researchers at Pharmaceutical Nanotechnology research group and Tampere University. The study provides key insights into the role of lipid oxidation in cargo release from light-activated liposomes. These spherical lipid vesicles can [...]

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Ru(II) Oligothienyl Complexes with Fluorinated Ligands: Photophysical, Electrochemical, and Photobiological Properties

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Published in: Inorganic Chemistry Authors: Houston D. Cole, Abbas Vali, John A. Roque III, Ge Shi, Alisher Talgatov, Gurleen Kaur, Antonio Francés-Monerris, Marta E. Alberto, Colin G. Cameron, Sherri A. McFarland  

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Red-Light Activation of a Microtubule Polymerization Inhibitor via Amide Functionalization of the Ruthenium Photocage

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Published in: Angew Chem Int Ed Authors: Ludovic Bretin, Yurii Husiev, Vadde Ramu, Liyan Zhang, Matthijs Hakkennes, Selda Abyar, Andrew C. Johns, Sylvia E. Le Dévédec, Tania Betancourt, Alexander Kornienko, Sylvestre Bonnet Leiden University A ruthenium-based compound was developed for PACT (photoactivated chemotherapy), which unlike most existing PACT compounds, can be also activated with clinically relevant

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Near-infrared Absorbing Ru(II) Complexes Act as Immunoprotective Photodynamic Therapy (PDT) Agents Against Aggressive Melanoma

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Published in: Chemical Science Authors: Liubov M. Lifshits, A. Roque III, Prathyusha Konda, Susan Monro, Houston D. Cole, David von Dohlen, Susy Kim, Gagan Deep, Randolph P. Thummel, Colin G. Cameron, Shashi Gujar, Sherri A. McFarland    

Near-infrared Absorbing Ru(II) Complexes Act as Immunoprotective Photodynamic Therapy (PDT) Agents Against Aggressive Melanoma Read More »

Breaking the barrier: an osmium photosensitizer with unprecedented hypoxic phototoxicity for real world photodynamic therapy

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Published in: Chemical Science Authors: John A. Roque III, Patrick C. Barrett, Houston D. Cole, Liubov M. Lifshits, Ge Shi, Susan Monro, David von Dohlen, Susy Kim, Nino Russo, Gagan Deep, Colin G. Cameron, Marta E. Alberto, Sherri A. McFarland    

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