Category: Laser-sharp Research

Modulight Spotlights: LASER-SHARP RESEARCH – August 2026

Laser-sharp Research / 690 nm, antibiotic resistance, antibiotics, antimicrobial, antimicrobial resistance, in vitro, laser-sharp research, LaserSharpResearch, light activation, ML6600, MRSA, nanotechnology, photodynamics, targeted therapies, targetedtherapies / August 25, 2026

Modulight Spotlights: LASER-SHARP RESEARCH – August 2026 A fresh publication from Tayyaba Hasan lab at Massachusetts General Hospital and Harvard Medical School has introduced a new solution for antibiotic-resistant bacterial strains. The team developed photoactivatable nanocarriers to enable co-delivery of antibiotic minocycline together with a light-sensitive compound into bacterial cells. When activated with a low [...]

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Modulight Spotlights: LASER-SHARP RESEARCH – July 2026

Laser-sharp Research / drug delivery, liposomes, nanomaterials, nanomedicine, Paclitaxel, photo-oxidation, photothermal therapy, verteporfin / August 6, 2026

Modulight Spotlights: LASER-SHARP RESEARCH – July 2026 The Research Highlight of the Month goes to Eija Ilvesroiha and Professor Timo Laaksonen’s Laboratory of Pharmaceutical Nanotechnology at the University of Helsinki. Their new study investigated the release mechanisms of the chemotherapy drug paclitaxel from light-activated liposomes. These lipid-based carriers have the potential to deliver drugs to

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Modulight Spotlights: LASER-SHARP RESEARCH – June 2026

Laser-sharp Research / antibiotic resistance, antimicrobial, antimicrobial therapy, appendicitis, disinfection, in vitro, in vivo, intra-abdominal infection, laparoscopic surgery, laser therapy, laser-sharp research, methylene blue, ML7710, PDT, pediatric surgery, perforation, Photodynamic therapy, Photoimmunotherapy, photomedicine, translational research / June 22, 2026

Research teams led by Dr. Timothy Baran and Dr. Nicole Wilson investigated laser-activated methylene blue therapy for perforated appendicitis. Using the ML7710 laser system, the study demonstrated a feasible and safe resistance-independent antimicrobial treatment approach.

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Modulight Spotlights: LASER-SHARP RESEARCH – May 2026

Laser-sharp Research / immunology, immunotherapy, laser-sharp research, light activation, liposomes, ML6600, pancreatic cancer, Photoimmunotherapy / May 20, 2026

Modulight Spotlights: LASER-SHARP RESEARCH – May 2026 The research spotlight goes this month to Nimit Shah and the team from Dr. Girgis Obaid’s Lab Molecular Imaging and Optical Nanotherapeutics at University of Texas, Dallas. They developed and evaluated light-activated, verteporfin-containing liposomes for pancreatic cancer. This cancer is notoriously difficult to treat and more effective therapies are

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Modulight Spotlights: LASER-SHARP RESEARCH – April 2026

Laser-sharp Research / 689 nm, cancer, immunotherapy, IR700, laser therapy, laser-sharp research, ML7710, peptides, Photoimmunotherapy, targeted therapies, tumor / April 27, 2026

Modulight Spotlights: LASER-SHARP RESEARCH – April 2026 This month we are pleased to highlight new interesting article by Naoya Kondo and the team at Kansai Medical University in Japan. They developed a cancer cell-targeted photoimmunotherapy compound consisting of IR700 photoabsorber conjugated to bicyclic peptide. Use of small peptide could speed drug clearance from the body

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Modulight Spotlights: LASER-SHARP RESEARCH – March 2026

Laser-sharp Research / chemo resistance, in vitro, in vivo, laser-sharp research, ML7710, ML8500, National Cancer Institute, ovarian cancer, peritoneal carcinoma, photoimmunoconjugates, Photoimmunotherapy, targeted therapies, University of Maryland / March 12, 2026

Modulight Spotlights: LASER-SHARP RESEARCH – March 2026 The development of chemoresistance presents a major challenge in treating peritoneal metastasis, which often occurs in advanced ovarian cancer. To tackle this, Kaitlyn Moore and teams at University of Maryland and National Cancer Institute evaluated photoimmunotherapy as a solution to inhibit a drug efflux pump on cancer cells

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Modulight Spotlights: LASER-SHARP RESEARCH – February 2026

Laser-sharp Research / antibodies, Cancer therapy, laser therapy, laser-sharp research, ML7710, next generation therapies, peptides, Photoimmunotherapy, tumor / February 27, 2026

Modulight Spotlights: LASER-SHARP RESEARCH – February 2026 This month, we are highlighting promising work by Professor Hirofumi Hanaoka’s team at Kansai Medical University, Photo-ImmunoTherapy Research Institute. They developed a novel peptide-based photoimmunotherapy drug that targets PD-L1, which is expressed on many types of cancer cells. Preclinical experiments showed significant suppression of tumor growth and an

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Modulight Spotlights: LASER-SHARP RESEARCH – January 2026

Laser-sharp Research / apoptosis, BPD, cancer, ferroptosis, in vitro, in vivo, laser-sharp research, light activation, ML6600, ovarian cancer, Photoimmunotherapy, photosensitizer / January 28, 2026

Modulight Spotlights: LASER-SHARP RESEARCH – January 2026 The highlight of the month goes to teams of researchers led by Prof. Imran Rizvi at University of North Carolina at Chapel Hill. Their latest publication shows that certain light-activated therapy with BPD photosensitizer and ML6600 laser can induce ferroptosis-like cell death, including formation of lipid peroxides, in

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Modulight Spotlights: LASER-SHARP RESEARCH – December 2025

Laser-sharp Research / imaging, in vitro, in vivo, laser-sharp research, ML6600, multi-wavelength, oxygen, Photodynamic therapy, treatment guidance, treatment monitoring, tumor, ultrasound / December 30, 2025

Deeksha Sankepalle and the group at Tufts University, USA developed an advanced multi-wavelength photoacoustic imaging system. It integrates a pulsed, tunable laser with an ultrasound acquisition platform to provide functional 3D imaging. The system enables real-time, non-invasive, high-resolution imaging of tumor vasculature by tracking oxygen saturation in the tumor.

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