ML8500

Harnessing liposomal nanocellulose hydrogel for NIR-light driven on-demand drug delivery

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Published in: Carbohydrate Polymer Technologies and Applications Authors: Puja Gangurde, Zahra Gounani, Jacopo Zini, Roberta Teixeira Polez, Monika Osterberg, Patrick Lauren, Tatu Lajunen, Timo Laaksonen  

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ML8500 – automatic biomedical illumination

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ML8500 Automatic biomedical illumination system ML8500 is the world's most versatile illumination device for in-vitro studies. ML8500 can support up to 7 different wavelengths simultaneously, flexible control of illumination parameters, and built-in incubation chamber for cells studies in normoxic and hypoxic conditions. Researcher operating ML8500 at Modulight's Biomedical Laboratories Request quotation! Automatic system for illuminating

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Modulight Spotlights: LASER-SHARP RESEARCH – October 2024

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Modulight Spotlights: LASER-SHARP RESEARCH – October 2024 This month, we are highlighting new findings published in RSC Materials Advances by Olga Lem, Roosa Kekki and researchers at Pharmaceutical Nanotechnology research group and Tampere University. The study provides key insights into the role of lipid oxidation in cargo release from light-activated liposomes. These spherical lipid vesicles can

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Modulight Spotlights: LASER-SHARP RESEARCH – September 2024

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University of Maryland and Modulight have published together a new research study about the mechanisms of cancer drug resistance. Drug resistance is a leading cause of treatment failure and often has dramatic consequences for survival of cancer patients.

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Ru(II) Oligothienyl Complexes with Fluorinated Ligands: Photophysical, Electrochemical, and Photobiological Properties

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Published in: Inorganic Chemistry Authors: Houston D. Cole, Abbas Vali, John A. Roque III, Ge Shi, Alisher Talgatov, Gurleen Kaur, Antonio Francés-Monerris, Marta E. Alberto, Colin G. Cameron, Sherri A. McFarland  

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Development of thermosensitive liposomes with the help of ML8500

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Background The proper delivery and release of therapeutic drugs to a specific site or cell type is one of the main challenges in the treatment of diseases. Liposomes, which are vesicles composed of lipids, serve as carriers for drug delivery thanks to their long circulation time. This results to reduced toxicity in healthy tissues and

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Co-Packaged PARP inhibitor and photosensitizer for targeted photo-chemotherapy of 3D ovarian cancer spheroids

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Published in: Cell & Bioscience Authors: Aaron Sorrin, Anika Dasgupta, Kathryn McNaughton, Carla Arnau Del Valle, Keri Zhou, Cindy Liu, Dana M. Roque & Huang Chiao Huang Within the last decade, poly(ADP-ribose) polymerase inhibitors (PARPi) have emerged in the clinic as an effective treatment for numerous malignancies. Preclinical data have demonstrated powerful combination effects of PARPi

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