in vitro

Modulight Spotlights: LASER-SHARP RESEARCH – January 2025

Kobayashi et al. at NIH developed a therapy which results in tumor cell membrane destruction and immunogenic cell death. When activated with the ML7710 laser, there was proven efficacy against various cancer cell types including pancreatic, oral, breast, and ovarian cancer.

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Tissue factor targeted near‑infrared photoimmunotherapy: a versatile therapeutic approach for malignancies

Published in: Cancer Immunology, Immunotherapy Authors: Seiichiro Takao, Hiroshi Fukushima, Aki Furusawa, Takuya Kato, Shuhei Okuyama, Makoto Kano, Hiroshi Yamamoto, Motofumi Suzuki, Miyu Kano, Peter L. Choyke, Hisataka Kobayashi  

Tissue factor targeted near‑infrared photoimmunotherapy: a versatile therapeutic approach for malignancies Read More »

Self-Assembled Verteporfin Nanoparticles for Photodynamic and Light-Independent Therapy in Glioblastoma

Published in: Advanced NanoBioMed Research Authors: John A. Quinlan, Kaylin Baumiller, Anandita Gaur, Wen-An Chiou, Robert W. Robey, Michael M. Gottesman, Huang-Chiao Huang  

Self-Assembled Verteporfin Nanoparticles for Photodynamic and Light-Independent Therapy in Glioblastoma Read More »

Modulight Spotlights: LASER-SHARP RESEARCH – September 2024

University of Maryland and Modulight have published together a new research study about the mechanisms of cancer drug resistance. Drug resistance is a leading cause of treatment failure and often has dramatic consequences for survival of cancer patients.

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Screening of photosensitizers-ATP binding cassette (ABC) transporter interactions in vitro

Published in: Cancer Drug Resistance Authors: Shruti Vig1, Payal Srivastava1,#, Idrisa Rahman1,2,#, Renee Jaranson1, Anika Dasgupta1, Robert Perttilä3, Petteri Uusimaa3, Huang-Chiao Huang1  

Screening of photosensitizers-ATP binding cassette (ABC) transporter interactions in vitro Read More »

Modulight Spotlights: LASER-SHARP RESEARCH – June 2024

A promising new therapy against viruses was developed at University of Manitoba and Theralase Technologies. The study evaluated antiviral effectiveness of a cancer drug (Ruvidar), activated with Modulight’s ML6600 green laser.

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Ru(II) Oligothienyl Complexes with Fluorinated Ligands: Photophysical, Electrochemical, and Photobiological Properties

Published in: Inorganic Chemistry Authors: Houston D. Cole, Abbas Vali, John A. Roque III, Ge Shi, Alisher Talgatov, Gurleen Kaur, Antonio Francés-Monerris, Marta E. Alberto, Colin G. Cameron, Sherri A. McFarland  

Ru(II) Oligothienyl Complexes with Fluorinated Ligands: Photophysical, Electrochemical, and Photobiological Properties Read More »

Near‐infrared photoimmunotherapy targeting PD‐L1: Improved efficacy by preconditioning the tumor microenvironment

Published in: Cancer Science Authors: Fuyuki F. Inagaki, Makoto Kano, Aki Furusawa, Takuya Kato, Ryuhei Okada, Hiroshi Fukushima, Seiichiro Takao, Shuhei Okuyama, Peter L. Choyke, Hisataka Kobayashi  

Near‐infrared photoimmunotherapy targeting PD‐L1: Improved efficacy by preconditioning the tumor microenvironment Read More »

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