The effect of light sensitizer localization on the stability of indocyanine green liposomes

Published in: Journal of Controlled Release

Authors: Tatu Lajunen, Riikka Nurmi, Danny Wilbie, Teemu Ruoslahti, Niklas G. Johansson, Ossi Korhonen, Tomasz Rog, Alex Bunker, Marika Ruponen, Arto Urtti

 

Targeted delivery of drugs using external light trigger is feasible in light-accessible organs, e.g. eye and skin, and it may offer several benefits compared to passive drug leakage from the drug carrier. The research group has used ML6600 laser and illumination kit (MLAKIT) for light-triggered release studies of calcein from ICG liposomes to optimize the liposome composition to be novel light-triggered drug carrier for PDT.

 

Read the article here