Tag: liposomes

Harnessing liposomal nanocellulose hydrogel for NIR-light driven on-demand drug delivery

Scientific papers / 808 nm, drug delivery, drug distribution, hydrogels, in vitro, liposomes, ML8500, nanoparticles, PDT, University of Helsinki

Published in: Carbohydrate Polymer Technologies and Applications Authors: Puja Gangurde, Zahra Gounani, Jacopo Zini, Roberta Teixeira Polez, Monika Osterberg, Patrick Lauren, Tatu Lajunen, Timo Laaksonen

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ML8500 – automatic biomedical illumination

product pages / biomedical, illumination, illumination kit, laser illumination, liposomes, microplates, ML8500, petri dish, photosensitizer, sequential, well plates

ML8500 Automatic biomedical illumination system ML8500 is the world's most versatile illumination device for in-vitro studies. ML8500 can support up to 7 different wavelengths simultaneously, flexible control of illumination parameters, and built-in incubation chamber for cells studies in normoxic and hypoxic conditions. Researcher operating ML8500 at Modulight's Biomedical Laboratories Request quotation! Automatic system for illuminating

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Modulight Spotlights: LASER-SHARP RESEARCH – October 2024

Laser-sharp Research / cancer treatment, drug delivery, hypoxia, laser-sharp research, light activation, liposomes, ML8500, normoxia, University of Helsinki

Modulight Spotlights: LASER-SHARP RESEARCH – October 2024 This month, we are highlighting new findings published in RSC Materials Advances by Olga Lem, Roosa Kekki and researchers at Pharmaceutical Nanotechnology research group and Tampere University. The study provides key insights into the role of lipid oxidation in cargo release from light-activated liposomes. These spherical lipid vesicles can

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Development of thermosensitive liposomes with the help of ML8500

Application Note / 808 nm, application note, drug delivery, drug discovery, illumination system, in vitro, indocyanine green, light activation, liposomes, ML6600, ML8500, MLAKIT, University of Helsinki

Background The proper delivery and release of therapeutic drugs to a specific site or cell type is one of the main challenges in the treatment of diseases. Liposomes, which are vesicles composed of lipids, serve as carriers for drug delivery thanks to their long circulation time. This results to reduced toxicity in healthy tissues and

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Development of Robust Cationic Light-Activated Thermosensitive Liposomes: Choosing the Right Lipids

Scientific papers / 808 nm, in vitro, light activation, liposomes, ML8500, University of Helsinki

Published in: Molecular Pharmaceutics Authors: Puja Gangurde, Mohammad Mahmoudzadeh, Zahra Gounani, Artturi Koivuniemi, Patrick Laurén, Tatu Lajunen, Timo Laaksonen

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Transient fluid flow improves photoimmunoconjugate delivery and photoimmunotherapy efficacy

Scientific papers / 690 nm, benzoporphyrin, cetuximab, drug delivery, in vitro, liposomes, ML6600, oncology, ovarian cancer, PDT, peritoneal cavity, photoimmunoconjugates, Photoimmunotherapy, photosensitizer

Published in: iScience Authors: Aaron J. Sorrin, Keri Zhou, Katherine May, Cindy Liu, Kathryn McNaughton, Idrisa Rahman, Barry J. Liang, Imran Rizvi, Dana M. Roque, Huang-Chiao Huang

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Light-induced cytotoxicity in cells utilizing an automated well plate illuminator

Scientific papers / ARPE-19, BIOS, drug delivery, hypoxia, illumination system, liposomes, ML8500, Modulight authors, nanotechnology, plate reader, SPIE BIOS 2023

Presented in: SPIE BIOS 2023 Authors: Laura Vesala, Robert Perttilä, Elias Kokko, Johannes Kivelä, Lasse Orsila, Petteri Uusimaa

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Modulight Spotlights: LASER-SHARP RESEARCH – February 2023

Laser-sharp Research / cell culture, flow chamber, flowchamber, in vitro, in vivo, laser-sharp research, light activation, liposomes, ML6500

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Light-induced drug delivery with indocyanine green liposomes

Application Note / 810 nm, bayer, Cancer therapy, drug delivery, drug discovery, ICG, in vitro, indocyanine green, liposomes, ML6500, ML6600, MLAKIT, ophthalmic cancers, University of Helsinki, vitreous

Introduction to light-controlled drug delivery systems Study description It is important that light-triggered liposomes efficiently release their contents, while the liposome stability should be maintained in the absence of laser light. The aim of this study is to determine how liposomal stability and drug release are affected by liposomal formulation. Indocyanine green was used as the light-sensitizing compound

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