Published in: International Journal of Pharmaceutics Authors: Eija Ilvesroiha, Suvi Heinonen, Riikka Rimmistö, Timo Oksanen, Nikita Durandin, Alex Bunker, Artturi Koivuniemi, Tatu Lajunen, Timo Laaksonen
Background The proper delivery and release of therapeutic drugs to a specific site or cell type is one of the main challenges in the treatment of diseases. Liposomes, which are vesicles composed of lipids, serve as carriers for drug delivery thanks to their long circulation time. This results to reduced toxicity in healthy tissues and
Development of thermosensitive liposomes with the help of ML8500 Read More »
Published in: Cancer Immunology, Immunotherapy Authors: Ruben V. Huis in ‘t Veld, Sen Ma, Rhonda C. Kines, Anneli Savinainen, Cadmus Rich, Ferry Ossendorp, Martine J. Jager
Introduction to light-controlled drug delivery systems Study description It is important that light-triggered liposomes efficiently release their contents, while the liposome stability should be maintained in the absence of laser light. The aim of this study is to determine how liposomal stability and drug release are affected by liposomal formulation. Indocyanine green was used as the light-sensitizing compound
Light-induced drug delivery with indocyanine green liposomes Read More »
Photothermal therapy efficiency Human ovarian cancer cells were plated on Petri dishes and incubated with platinum nanoparticles of varying sizes between 30 and 70 nm. After 24-hour incubation, irradiation was performed using a Modulight ML6600 laser at 808 nm together with an illumination kit (MLAKIT) tailored for Petri dish illumination. A small area of the dish
Photothermal therapy with platinum nanoparticles Read More »
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Protected: Vision-sparing targeted phototherapy for uveal melanoma Read More »
Published in: Cancer Immunology Research Authors: Rhonda C Kines, Cynthia D Thompson, Sean Spring, Zhenyu Li, Elisabet de los Pinos, Stephen Monks, John T Schiller Related application note: Vision-sparing targeted phototherapy for uveal melanoma
