Novel ophthalmic laser system paired with focal electroretinography for subthreshold laser therapy of DME

Presented in: SPIE BIOS 2023

Authors: Jukka-Pekka AlankoEero KoivumäkiLaura VesalaJohannes KiveläZoe YlöniemiPetteri UusimaaOssi KaikkonenTeemu TurunenJaakko NieminenJani Tirronen


In the field of ophthalmic treatments, subthreshold laser therapy (SLT) has shown promise in addressing retinal diseases like diabetic macular edema (DME) and age-related macular degeneration (AMD). However, the precise control of therapeutic temperatures is challenging due to variations in individual eye characteristics. Modulight and Maculaser have addressed this issue with their innovative ML6710i device. This device utilizes a combination of laser beams to achieve precise thermal dosimetry-controlled retinal laser treatments. By monitoring focal electroretinography (fERG) from the target tissue, temperature-dependent changes are analyzed, ensuring accurate therapeutic temperatures for each patient. The device features an iOS-based graphical user interface (GUI), live fundus view, and data storage in the Modulight Cloud. While initial testing on a human subject demonstrated success in fERG signal measurement, ongoing device development includes clinical trials.


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