Tag: BIOS

Robust and field-replaceable multiwavelength laser system for flow cytometry

Flow cytometry requires stable, precisely-shaped laser light for accurate fluorescence detection. Modulight’s ML6640 laser engine integrates automatic beam alignment and built-in beam shaping to deliver stable, uniform illumination over time. This work presents updated characterization results of the ML6640, including beam uniformity, optical stability, and alignment performance.

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Improving efficiency and stability of power-scalable light engine for super-resolution microscopy

Scientific papers / 355 nm, 405 nm, 488 nm, 532 nm, 561 nm, 638 nm. lowe speckle, BIOS, flat-top beam profile, fluorophores, low-noise, ML6600, multi-color imaging, SPIE, SRM, super-resolution microscopy / March 5, 2026

This paper presents recent enhancements to Modulight’s power-scalable light engine for super-resolution microscopy, improving power stability, dynamic range, and overall robustness to meet the demanding requirements of advanced biological imaging applications.

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Power scalable speckle-free multi-wavelength light engine for super-resolution microscopy

Scientific papers / 355 nm, 405 nm, 488 nm, 561 nm, 638 nm, BIOS, imaging, laser engine, microscopy, ML6600, Modulight authors, narrow linewidth, Photonics West, speckle removal, SPIE, super-resolution microscopy / March 19, 2025

Published in: SPIE BIOS 2025 Authors: Anna Essauolva, Sergei Kuehn, Visa Kaivosoja, Andrei Fedotov, Petteri Uusimaa

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Fluorescence-guided, targeted photochemotherapy of peritoneal carcinomatosis

Scientific papers / BIOS, carcinomatosis, fluorescence-guided surgery, ML6600, ML7710, Modulight authors, PDT, peritoneal cavity, SPIE, SPIE BIOS 2023, targeted therapies, UMD / March 17, 2023

Presented in: SPIE BIOS 2023 Authors: Barry J. Liang, Robert Perttilä, Sumiao Pang, Chen-Hua Ma, Payal Srivastava, Brandon Gaitan, Aaron J. Sorrin, Zoe Ylöniemi, Dana Roque, Tayyaba Hasan, Petteri Uusimaa, Huang-Chiao Huang

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Novel ophthalmic laser system paired with focal electroretinography for subthreshold laser therapy of DME

Scientific papers / 689 nm, age-related macular degeneration, AMD, BIOS, clinical trials, DME, fERG, focal electroretinography, fundus imaging, ML6710i, Modulight authors, Modulight Cloud, ophthalmic treatments, retinal diseases, SPIE, SPIE BIOS 2023, thermal dosimetry / March 17, 2023

Presented in: SPIE BIOS 2023 Authors: Jukka-Pekka Alanko, Eero Koivumäki, Laura Vesala, Johannes Kivelä, Zoe Ylöniemi, Petteri Uusimaa, Ossi Kaikkonen, Teemu Turunen, Jaakko Nieminen, Jani Tirronen

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Laser platform and light delivery optimization for bladder cancer treatment with a novel photosensitive drug

Scientific papers / BIOS, bladder cancer, cetuximab, conjugated to the photosensitizer, cystoscopy, drug delivery, endoscopy, fluorescent imaging, fluorophore activation, light delivery, ML7710, Modulight authors, Modulight Cloud, NMIBCSPIE, PDT, Photodynamic therapy, SPIE, SPIE BIOS 2023 / March 14, 2023

Presented in: SPIE BIOS 2023 Authors: Zoe Ylöniemi, Elias Kokko, Visa Kaivosoja, Ana Colucci, Eerika Suokas, Jukka-Pekka Alanko, Petteri Uusimaa, Modulight Corp.

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Novel ophthalmic PDT laser platform to target oncology and various other retinal indications

Scientific papers / age-related macular degeneration, AMD, BIOS, CSC, CSR, drug delivery, ML6710i, Modulight authors, Modulight Cloud, nAMD, oncology, ophthalmology, PCV, PDT, Retina, SLA, slit lamp adapter, SPIE, SPIE BIOS 2023 / March 14, 2023

Presented in: SPIE BIOS 2023 Authors: Laura Vesala, Eero Koivumäki, Jukka-Pekka Alanko, Timo Tanila, Ivan Baldin, Zoe Ylöniemi, Petteri Uusimaa, Modulight Corp.

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Optimization of light delivery for non-muscle invasive bladder cancer PDT

Scientific papers / BIOS, bladder cancer, drug delivery, light delivery, ML7710, Modulight authors, NMIBC, oncology, PDT, SPIE, SPIE BIOS 2023 / March 14, 2023

Presented in: SPIE BIOS 2023 Authors: Elias Kokko, Robert Perttilä, Zoe Ylöniemi, Visa Kaivosoja, Jukka-Pekka Alanko, Petteri Uusimaa, Modulight Corp.

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Light-induced cytotoxicity in cells utilizing an automated well plate illuminator

Scientific papers / ARPE-19, BIOS, drug delivery, hypoxia, illumination system, liposomes, ML8500, Modulight authors, nanotechnology, plate reader, SPIE, SPIE BIOS 2023 / March 7, 2023

Presented in: SPIE BIOS 2023 Authors: Laura Vesala, Robert Perttilä, Elias Kokko, Johannes Kivelä, Lasse Orsila, Petteri Uusimaa

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