The spotlight of the month goes to Andrew Langley et al. at Tufts University, USA, for their impressive work in leveraging photoacoustic imaging for real-time monitoring of phototherapy. Photoacoustic imaging is 3D, non-ionizing and non-invasive imaging method, based on optical absorption that creates pressure waves detected by ultrasound transducer.
Modulight Spotlights: LASER-SHARP RESEARCH – July 2025 Read More »
Chen-Hua Ma et al. Optical Therapeutics & Nanotechnology Laboratory at University of Maryland combined photoimmunotherapy with ethanol ablation to achieve improved drug retention and light penetration, especially important for treating pigmented organs like liver and pancreas. Modulight’s ML7710 laser was used for both therapeutic activation of the nanoconstruct, as well as for theranostic monitoring of the process.
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Published in: Bioengineering & Translational Medicine Authors: Chen-Hua Ma, Jeffrey Yang, John A. Quinlan, Kathryn McNaughton, Michele L. Kaluzienski, Tessa Hauser, Matthew F. Starost, Jenna L. Mueller, Huang-Chiao Huang
Published in: Photochemistry and Photobiology Authors: Sumeyra Gokalp, Marvin Xavierselvan, Mohammad Forhad Khan, Ronak Shethia, Sima Khani, Ryan H. Riddell, Anna V. Krasnoslobodtseva, Srivalleesha Mallidi, Michelle Foster
Coleman et al. / MSKCC developed a vascular-targeted therapy for bladder cancer. Padeliporfin is illuminated with the Modulight’s ML7710 laser, resulting in selective ablation of bladder tumors, without harming the healthy bladder tissue.
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A. Lepland and the teams at University of Tartu, Estonia and Veneto Institute of Oncology, Italy, developed a new immunotherapy for triple negative breast cancer, using Modulight ML6000-series laser. Tumor growth slowed down and the cancer’s spreading to the lungs was suppressed.
Modulight Spotlights: LASER-SHARP RESEARCH – February 2025 Read More »
New findings in prostate cancer research were reported by Xinning Wang and team at Case Western University, Comprehensive Cancer Center. Using ML7710 laser at 672 nm for activation of the drug, they were able to dramatically improve therapeutic effect in prostate cancer models.
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Deadliest cancer Precision with photoactivation Photoimmunotherapy with ML7710 offers a clinical therapeutic option for NSCLC patients even with advanced disease stage. Besides laser light, this therapy involves photoactivated drug, which can be activated precisely at the tumor site with laser fibers, hence minimizing drug effects to healthy tissues. Smaller invasiveness compared to surgery can enable
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Introduction to light-controlled drug delivery systems Study description It is important that light-triggered liposomes efficiently release their contents, while the liposome stability should be maintained in the absence of laser light. The aim of this study is to determine how liposomal stability and drug release are affected by liposomal formulation. Indocyanine green was used as the light-sensitizing compound
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