Tag: pancreatic cancer

Modulight Spotlights: LASER-SHARP RESEARCH – May 2026

Laser-sharp Research / immunology, immunotherapy, laser-sharp research, light activation, liposomes, ML6600, pancreatic cancer, Photoimmunotherapy / May 20, 2026

Modulight Spotlights: LASER-SHARP RESEARCH – May 2026 The research spotlight goes this month to Nimit Shah and the team from Dr. Girgis Obaid’s Lab Molecular Imaging and Optical Nanotherapeutics at University of Texas, Dallas. They developed and evaluated light-activated, verteporfin-containing liposomes for pancreatic cancer. This cancer is notoriously difficult to treat and more effective therapies are [...]

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Modulight Spotlights: LASER-SHARP RESEARCH – June 2025

Laser-sharp Research / Cancer therapy, fluorescence, in vitro, in vivo, laser-sharp research, liver cancer, ML7710, pancreas, pancreatic cancer, theranostics, University of Maryland / June 3, 2025

Chen-Hua Ma et al. Optical Therapeutics & Nanotechnology Laboratory at University of Maryland combined photoimmunotherapy with ethanol ablation to achieve improved drug retention and light penetration, especially important for treating pigmented organs like liver and pancreas. Modulight’s ML7710 laser was used for both therapeutic activation of the nanoconstruct, as well as for theranostic monitoring of the process.

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Synergizing photodynamic therapy and ethanol ablation: Light-activatable sustained-exposure ethanol injection technology for enhanced tumor ablation

Scientific papers / Cancer therapy, fluorescence, in vitro, in vivo, liver cancer, ML7710, pancreas, pancreatic cancer, theranostics, University of Maryland / May 15, 2025

Published in: Bioengineering & Translational Medicine Authors: Chen-Hua Ma, Jeffrey Yang, John A. Quinlan, Kathryn McNaughton, Michele L. Kaluzienski, Tessa Hauser, Matthew F. Starost, Jenna L. Mueller, Huang-Chiao Huang

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Intratumoral interleukin-15 improves efficacy of near-infrared photoimmunotherapy

Scientific papers / 690 nm, colon cancer, IL-15, immunotherapy, in vitro, in vivo, interleukin, intratumoral, ML7710, pancreatic cancer, Photoimmunotherapy / July 18, 2023

Published in: Molecular Cancer Therapeutics Authors: Hiroshi Fukushima, Aki Furusawa, Takuya Kato, Hiroaki Wakiyama, Seiichiro Takao, Shuhei Okuyama, Peter L. Choyke, Hisataka Kobayashi

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Optimized light delivery in pancreatic cancer

Application Note / 689 nm, in vivo, interstitial, ML7710, pancreas, pancreatic cancer, phototherapy, tumor, University of California at Irvine / November 10, 2021

Motivation for the study Efficient light delivery to the whole tumor is one of the main aspects of phototherapy. The efficacy of phototherapy has been demonstrated for several cancers via superficial illumination. Interstitial illumination could enhance light delivery deeper inside the tumor and potentially result in more effective tumor eradication. Hence, the aim of this

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