Tag: vascular-targeted PDT

Selectivity and anti-tumor immune elevation by vascular-targeted photodynamic therapy of mouse orthotopic bladder cancer model

Scientific papers / 753 nm, bladder cancer, cancer treatment, in vivo, Memorial Sloan Kettering Cancer Center, ML7710, PDT, vascular-targeted PDT, WST11 / March 6, 2025

Published in: Photochemistry and Photobiology Authors: Jie Chen, Natalia Kudinova, Rebecca Dubrovsky, Jasmine Thomas, Karan Nagar, Lucas Nogueira, Avigdor Scherz, Kwanghee Kim, Jonathan Coleman Vascular-targeted therapy (VTP) with WST11 was evaluated for muscle-invasive bladder cancer treatment in orthotopic mouse model for safety and efficacy. Whole bladder was illuminated with a frontal diffuser connected to ML7710

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Feasibility and Pathologic Outcomes of Peripheral Lung Vascular Targeted Photodynamic Therapy in a Normal Porcine Lung Model

Scientific papers / 753 nm, bronchoscopy, in vivo, Lung cancer, Memorial Sloan Kettering Cancer Center, ML7710, padeliporfin, vascular-targeted PDT, Weizmann Institute of Science / August 28, 2024

Published in: Chest Pulmonary Authors: Jason Beattie, Mario Ghosn, Kwanghee Kim, Raymond Parrish, Jie Chen, Stephen B. Solomon, Sebastien Monette, Christopher Cheleuitte-Nieves, Reza Bergemann, Mohit Chawla, Bryan C. Husta, Or Kalchiem-Dekel, Yaniv Cohen, Dina Preise, Zachary Sacks, Avigdor Scherz, Lonny Yarmus, Jonathan A. Coleman, Robert P. Lee

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Comparative study of immune response to local tumor destruction modalities in a murine breast cancer model

Scientific papers / 755 nm, breast cancer, immunotherapy, in vivo, Memorial Sloan Kettering Cancer Center, ML7710, PDT, T cells, Tookad, tumor, vascular-targeted PDT / June 18, 2024

Published in: Frontiers in Oncology Authors: Sadna Budhu, Kwanghee Kim, Wesley Yip, Stephen La Rosa, Sylvia Jebiwott, Liqun Cai, Aliya Holland, Jasmine Thomas, Dina Preise, Alex Somma, Benjamin Gordon, Avigdor Scherz, Jedd D. Wolchok, Joseph Erinjeri, Taha Merghoub, Jonathan A. Coleman

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High-resolution optoacoustic imaging of tissue responses to vascular-targeted therapies

Scientific papers / hemoglobin, imaging, ML7710, PDT, preclinical, RSOM, Tookad, vascular-targeted PDT, vascularization / March 12, 2020

Published in: Nature Biomedical Engineering Authors: Katja Haedicke, Lilach Agemy, Murad Omar, Andrei Berezhnoi, Sheryl Roberts, Camila Longo-Machado, Magdalena Skubal, Karan Nagar, Hsiao-Ting Hsu, Kwanghee Kim, Thomas Reiner, Jonathan Coleman, Vasilis Ntziachristos, Avigdor Scherz, Jan Grimm

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WST11 Vascular Targeted Photodynamic Therapy Effect Monitoring by Multispectral Optoacoustic Tomography (MSOT) in Mice

Scientific papers / 753 nm, ML7710, PDT, Photodynamic therapy, preclinical, renal cancer, Tookad, vascular-targeted PDT, WST11 / January 1, 2018

Published in: Theranostics Authors: Volker Neuschmelting, Kwanghee Kim, Jaber Malekzadeh-Najafabadi, Sylvia Jebiwott, Jaya Prakash, Avigdor Scherz, Jonathan A. Coleman, Moritz F. Kircher, Vasilis Ntziachristos

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