Tag: targeted therapy

Modulight Spotlights: LASER-SHARP RESEARCH – September 2025

Laser-sharp Research / cancer, immunotherapy, in vitro, in vivo, laser-sharp research, ML7710, noveltherapies, Photoimmunotherapy, targeted therapy

Published in journal Cancer Medicine, the study shows that the therapeutic effect of photoimmunotherapy is highly dependent on the used light irradiation conditions. Application of the ML7710 medical laser at different durations and powers resulted in highest anti-tumor effect with increased light dose but lowering fluence rate below what is currently used in clinic.

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Modulight Spotlights: LASER-SHARP RESEARCH – August 2025

Laser-sharp Research / breast cancer, cancer, immunotherapy, in vitro, in vivo, laser-sharp research, ML7710, NIH, Photoimmunotherapy, targeted therapy

Laser-sharp research of the month is by Furusawa et al. at Center for Cancer Research, National Cancer Institute, USA. The discovery, published in Annals of Medicine, showed the potential of photoimmunotherapy for treating breast cancer. To expand the usefulness of photoimmunotherapy outside the clinically approved head & neck indication, the new therapy targeted epithelial cell adhesion molecule in breast cancer.

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Modulight Spotlights: LASER-SHARP RESEARCH – May 2024

Laser-sharp Research / laser-sharp research, ML6600, ovarian cancer, Photoimmunotherapy, primary cultures, targeted therapy

Professor Bryan Spring and his team at Northeastern University has shown promising results for improved photoimmunotherapy protocols using patient-derived ovarian cancer cells, using Modulight’s ML6000-series laser.

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Immune checkpoint inhibition combined with targeted therapy using a novel virus‑like drug conjugate induces complete responses in a murine model of local and distant tumors

Scientific papers / 690 nm, AU-011, immune checkpoints, in vitro, in vivo, ML6600, MLAKIT, oncology, Photoimmunotherapy, targeted therapy, virus-like conjugates

Published in: Cancer Immunology, Immunotherapy Authors: Ruben V. Huis in ‘t Veld, Sen Ma, Rhonda C. Kines, Anneli Savinainen, Cadmus Rich, Ferry Ossendorp, Martine J. Jager

Immune checkpoint inhibition combined with targeted therapy using a novel virus‑like drug conjugate induces complete responses in a murine model of local and distant tumors Read More »