Tag: PPIX

Light penetration depth in brain with different photosensitizers

Application Note / 5-ALA, 635 nm, 689 nm, BPD, brain cancer, glioblastoma, ML6600, PDT, Photoimmunotherapy, PIT, PPIX, University of Maryland, verteporfin / October 28, 2021

Motivation for the study Glioblastoma is the most aggressive and lethal brain cancer with an average prognosis of 15 months. Fluorescence-guided surgery (FGS) for glioblastoma was FDA-approved in 2017, while photodynamic therapy (PDT) remains an active area of clinical investigation with very promising results so far. The aim of PDT is to eradicate the […]

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ML7710 for glioblastoma treatment

Application Note / 5-ALA, brain cancer, fluorescence-guided surgery, glioblastoma, ML7710, PDT, Photodynamic therapy, PPIX, reactive oxygen species, UKM, University Hospital Münster / May 25, 2021

Customer case Research by: University Hospital Münster provides cutting-edge medical treatments for patients all over the world. The department of neurosurgery provides a full spectrum of neurosurgical care with interdisciplinary vascular and neuro-oncological specialization. Modulight products: ML7710, ML7710i Laser use: Randomized controlled PDT trials for both newly diagnosed and recurrent glioblastoma, as well as compassionate care

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Cloud-based medical laser platform for phototherapy and treatment monitoring for glioblastoma

Scientific papers / 5-ALA, 635 nm, AI, cancer treatment, fluorescence, glioblastoma, PDT, Photodynamic therapy, PPIX, treatment monitoring / March 5, 2021

Presented in: SPIE BIOS 2021 Authors: Zoe Ylöniemi, Visa Kaivosoja, Juha Lemmetti, Timo Tanila, Eero Koivumäki, Lasse Orsila, Petteri Uusimaa

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Combination of ALA-induced fluorescence-guided resection and intraoperative open photodynamic therapy for recurrent glioblastoma: case series on a promising dual strategy for local tumor control

Scientific papers / 5-ALA, clinical, compassionate care, FGR, Fluorescence-guided resection, glioblastoma, ML7710, PDT, PPIX / January 24, 2020

Published in: Journal of Neurosurgery Authors: Stephanie Schipmann, Michael Müther, Louise Stögbauer, Sebastian Zimmer, Benjamin Brokinkel, Markus Holling, Oliver Grauer, Eric Suero Molina, Nils Warneke, Walter Stummer

Combination of ALA-induced fluorescence-guided resection and intraoperative open photodynamic therapy for recurrent glioblastoma: case series on a promising dual strategy for local tumor control Read More »