Tag: ML7710 | Page 10

Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging

Scientific papers / 690 nm, in vitro, in vivo, IRDye700, IRDye700DX, ML7710, PDT, preclinical, targeted cancer PDT, targeted therapies / January 20, 2020

Published in: Theranostics Authors: Henriette S. de Bruijn, Vida Mashayekhi, Tom J.L. Schreurs, Pieter B.A.A. van Driel, Gustav J. Strijkers, Paul J. van Diest, Clemens W.G.M. Lowik, Ann L.B. Seynhaeve, Timo L.M. ten Hagen, Jeanine J. Prompers, Paul M.P. van Bergen en Henegouwen, Dominic J. Robinson, Sabrina Oliveira

Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging Read More »

Irradiance controls photodynamic efficacy and tissue heating in experimental tumours: implication for interstitial PDT of locally advanced cancer

Scientific papers / 630 nm, Barrett's esophagus, esophageal cancer, H&N cancer, head & neck cancer, high-grade dysplasia, in vivo, iPDT, Lung cancer, ML6600, ML7710, PDT, photofrin, preclinical / October 24, 2018

Published in: British Journal of Cancer Authors: Gal Shafirstein, David A. Bellnier, Emily Oakley, Sasheen Hamilton, Michael Habitzruther, Lawrence Tworek, Alan Hutson, Joseph A. Spernyak, Sandra Sexton, Leslie Curtin, Steven G. Turowski, Hassan Arshad, Barbara Henderson

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ML7710 for lung cancer treatments at Roswell Park

Modulight in Media / Lung cancer, ML7710 / August 31, 2018

Treating lung cancer has been a huge challenge, but now, a treatment that’s been around for decades is being used in a new way, and the results so far have been encouraging. In this video thoraic surgeon Dr. Nwogu at Roswell Park Comprehensive Cancer Center explains the benefits of PDT treatment for lung cancer. A

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WST11 Vascular Targeted Photodynamic Therapy Effect Monitoring by Multispectral Optoacoustic Tomography (MSOT) in Mice

Scientific papers / 753 nm, ML7710, PDT, Photodynamic therapy, preclinical, renal cancer, Tookad, vascular-targeted PDT, WST11 / January 1, 2018

Published in: Theranostics Authors: Volker Neuschmelting, Kwanghee Kim, Jaber Malekzadeh-Najafabadi, Sylvia Jebiwott, Jaya Prakash, Avigdor Scherz, Jonathan A. Coleman, Moritz F. Kircher, Vasilis Ntziachristos

WST11 Vascular Targeted Photodynamic Therapy Effect Monitoring by Multispectral Optoacoustic Tomography (MSOT) in Mice Read More »

Photodynamic therapy for the treatment of atherosclerotic plaque: Lost in translation

Scientific papers / ML7710, PDT, Photodynamic therapy / November 28, 2016

Published in: Cardiovascular therapeutics Authors: Manish Jain, Matthieu Zellweger, Georges Wagnières, Hubert van den Bergh, Stéphane Cook, Marie-Noelle Giraud

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Fully automated illumination study series for modern cancer drug development

Application Note / breast cancer, drug development, drug discovery, in vitro, ML7710, ML8500, Roswell Park Cancer Institute, University of Sao Paulo / November 9, 2016

Fully automated illumination study series for modern cancer drug development In vitro cell viability and dose escalation study for developing photosensitive or photoactivated drugs using Modulight ML7710 medical laser and ML8500 automated illumination system. Experimental set up

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Disulfonated tetraphenyl chlorin (TPCS2a)-induced photochemical internalisation of bleomycin in patients with solid malignancies: a phase 1, dose-escalation, first-in-man trial

Scientific papers / 652 nm, clinical, H&N cancer, head & neck cancer, ML7710, Phase 1, Photochemical internalisation, TPCS2a / July 27, 2016

Published in: Lancet Oncology Authors: Ahmed A Sultan, Waseem Jerjes, Kristian Berg, Anders Høgset, Charles A Mosse, Rifat Hamoudi, Zaid Hamdoon, Celia Simeon, Dawn Carnell, Martin Forster, Colin Hopper

Disulfonated tetraphenyl chlorin (TPCS2a)-induced photochemical internalisation of bleomycin in patients with solid malignancies: a phase 1, dose-escalation, first-in-man trial Read More »

EGFR targeted nanobody–photosensitizer conjugates for photodynamic therapy in a pre-clinical model of head and neck cancer

Scientific papers / 690 nm, H&N cancer, head & neck cancer, IRDye700, ML7710, PDT, Photodynamic therapy, preclinical, targeted therapies / May 10, 2016

Published in: Journal of Controlled Release Authors: Pieter B.A.A. van Driel, Martin C. Boonstra, Maxime D. Slooter, Raimond Heukers, Marieke A. Stammes, Thomas J.A. Snoeks, Henriette S. de Bruijn, Paul J. van Diest, Alexander L. Vahrmeijer, Paul M.P. van Bergen en Henegouwen, Cornelis J.H. van de Velde, Clemens W.G.M. Löwik, Dominic J. Robinson, Sabrina Oliveira

EGFR targeted nanobody–photosensitizer conjugates for photodynamic therapy in a pre-clinical model of head and neck cancer Read More »

Photodynamic Therapy of Non–Small Cell Lung Cancer. Narrative Review and Future Directions

Scientific papers / cancer, interstitial, Lung cancer, ML7710, ML7710-PDT, PDT, Photodynamic therapy / February 1, 2016

Published in: Annals of the American Thoracic Society Authors: Gal Shafirstein 1,2, Athar Battoo 3, Kassem Harris 4, Heinz Baumann 5, Sandra O. Gollnick 1,6, Joerg Lindenmann 1,7, and Chukwumere E. Nwogu 3 1Photodynamic Therapy Center 2Department of Cell Stress Biology 3Department of Thoracic Surgery 4Department of Medicine, Interventional Pulmonology 5Department of Molecular and Cellular Biology, and 6Department of Immunology, Roswell Park Cancer Institute, Buffalo, New York; and 7Division

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