Memorial Sloan Kettering Cancer Center

Modulight Spotlights: LASER-SHARP RESEARCH – March 2025

Coleman et al. / MSKCC developed a vascular-targeted therapy for bladder cancer. Padeliporfin is illuminated with the Modulight’s ML7710 laser, resulting in selective ablation of bladder tumors, without harming the healthy bladder tissue.

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Selectivity and anti-tumor immune elevation by vascular-targeted photodynamic therapy of mouse orthotopic bladder cancer model

Published in: Photochemistry and Photobiology Authors: Jie Chen, Natalia Kudinova, Rebecca Dubrovsky, Jasmine Thomas, Karan Nagar, Lucas Nogueira, Avigdor Scherz, Kwanghee Kim, Jonathan Coleman  

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Feasibility and Pathologic Outcomes of Peripheral Lung Vascular Targeted Photodynamic Therapy in a Normal Porcine Lung Model

Published in: Chest Pulmonary Authors: Jason Beattie, Mario Ghosn, Kwanghee Kim, Raymond Parrish, Jie Chen, Stephen B. Solomon, Sebastien Monette, Christopher Cheleuitte-Nieves, Reza Bergemann, Mohit Chawla, Bryan C. Husta, Or Kalchiem-Dekel, Yaniv Cohen, Dina Preise, Zachary Sacks, Avigdor Scherz, Lonny Yarmus, Jonathan A. Coleman, Robert P. Lee  

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Comparative study of immune response to local tumor destruction modalities in a murine breast cancer model

Published in: Frontiers in Oncology Authors: Sadna Budhu, Kwanghee Kim, Wesley Yip, Stephen La Rosa, Sylvia Jebiwott, Liqun Cai, Aliya Holland, Jasmine Thomas, Dina Preise, Alex Somma, Benjamin Gordon, Avigdor Scherz, Jedd D. Wolchok, Joseph Erinjeri, Taha Merghoub, Jonathan A. Coleman  

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Vascular-targeted phototherapy study for prostate cancer

  Study protocol         Related Modulight products and Services ML7710 – Laser device suited for pre-clinical and clinical applications »      Related Publications WST11 Vascular Targeted Photodynamic Therapy Effect Monitoring by Multispectral Optoacoustic Tomography (MSOT) in Mice Volker Neuschmelting, Kwanghee Kim, Jaber Malekzadeh-Najafabadi, Sylvia Jebiwott, Jaya Prakash, Avigdor Scherz, Jonathan A Coleman, Moritz F Kircher, Vasilis Ntziachristos Theranostics, 2018,

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