Tag: laser-sharp research | Page 2

Modulight Spotlights: LASER-SHARP RESEARCH – August 2025

Laser-sharp Research / breast cancer, cancer, immunotherapy, in vitro, in vivo, laser-sharp research, ML7710, NIH, Photoimmunotherapy, targeted therapy / August 18, 2025

Laser-sharp research of the month is by Furusawa et al. at Center for Cancer Research, National Cancer Institute, USA. The discovery, published in Annals of Medicine, showed the potential of photoimmunotherapy for treating breast cancer. To expand the usefulness of photoimmunotherapy outside the clinically approved head & neck indication, the new therapy targeted epithelial cell adhesion molecule in breast cancer.

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Modulight Spotlights: LASER-SHARP RESEARCH – July 2025

Laser-sharp Research / Cancer therapy, imaging, in vitro, in vivo, laser-sharp research, ML6600, oxygen, photoacoutics, theranostics, treatment monitoring, ultrasound / July 22, 2025

The spotlight of the month goes to Andrew Langley et al. at Tufts University, USA, for their impressive work in leveraging photoacoustic imaging for real-time monitoring of phototherapy. Photoacoustic imaging is 3D, non-ionizing and non-invasive imaging method, based on optical absorption that creates pressure waves detected by ultrasound transducer.

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Modulight Spotlights: LASER-SHARP RESEARCH – June 2025

Laser-sharp Research / Cancer therapy, fluorescence, in vitro, in vivo, laser-sharp research, liver cancer, ML7710, pancreas, pancreatic cancer, theranostics, University of Maryland / June 3, 2025

Chen-Hua Ma et al. Optical Therapeutics & Nanotechnology Laboratory at University of Maryland combined photoimmunotherapy with ethanol ablation to achieve improved drug retention and light penetration, especially important for treating pigmented organs like liver and pancreas. Modulight’s ML7710 laser was used for both therapeutic activation of the nanoconstruct, as well as for theranostic monitoring of the process.

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Modulight Spotlights: LASER-SHARP RESEARCH – May 2025

Laser-sharp Research / anti-infection, antibiotic resistance, antimicrobial, bacterial infection, hydrogels, in vitro, infections, laser-sharp research, ML6600, photothermal therapy, wound healing / May 13, 2025

Cheng-Yu Lai et al. at Florida International University explores a solution for antibiotic-free wound healing. A photothermally controllable hydrogel was illuminated by NIR light from ML6600 laser, causing complete eradication of bacteria.

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Modulight Spotlights: LASER-SHARP RESEARCH – April 2025

Laser-sharp Research / drug delivery, imaging, in vitro, laser-sharp research, light activation, ML6600, nanoparticles, Photodynamic therapy, Photoimmunotherapy, verteporfin / April 30, 2025

Gokalp et al. from University of Massachusetts and Tufts University constructed an innovative liquid metal nanoparticle platform, which has tumor cell targeting and enhanced encapsulation of verteporfin. Charactierization in vitro with the help of ML6600 laser showed effective in vitro phototoxicity.

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Modulight Spotlights: LASER-SHARP RESEARCH – March 2025

Laser-sharp Research / bladder cancer, cancer, Cancer therapy, immune activation, immune response, immunotherapy, laser-sharp research, Memorial Sloan Kettering Cancer Center, ML7710, padeliporfin / March 19, 2025

Coleman et al. / MSKCC developed a vascular-targeted therapy for bladder cancer. Padeliporfin is illuminated with the Modulight’s ML7710 laser, resulting in selective ablation of bladder tumors, without harming the healthy bladder tissue.

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Modulight Spotlights: LASER-SHARP RESEARCH – February 2025

Laser-sharp Research / breast cancer, cancer, Cancer therapy, cancer treatment, immunology, immunotherapy, in vitro, in vivo, laser-sharp research, ML6600, photosensitizer, research, tumor, verteporfin / February 17, 2025

A. Lepland and the teams at University of Tartu, Estonia and Veneto Institute of Oncology, Italy, developed a new immunotherapy for triple negative breast cancer, using Modulight ML6000-series laser. Tumor growth slowed down and the cancer’s spreading to the lungs was suppressed.

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Modulight Spotlights: LASER-SHARP RESEARCH – January 2025

Laser-sharp Research / cancer, immunology, immunotherapy, in vitro, in vivo, laser-sharp research, LaserSharpResearch, light activation, ML7710, research, targeted therapies / January 22, 2025

Kobayashi et al. at NIH developed a therapy which results in tumor cell membrane destruction and immunogenic cell death. When activated with the ML7710 laser, there was proven efficacy against various cancer cell types including pancreatic, oral, breast, and ovarian cancer.

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Modulight Spotlights: LASER-SHARP RESEARCH – December 2024

Laser-sharp Research / clinical, laser-sharp research, mesothelioma, ML7710, personalized medicine, pulmonology, real-time monitoring / December 17, 2024

Timothy C. Zhu et al. at University of Pennsylvania investigated the use of PDT for mesothelioma, an aggressive lung cancer. 24 malignant pleural mesothelioma patients were treated with photodynamic therapy using Photofrin and the ML7710 laser.

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