imaging

Modulight Spotlights: LASER-SHARP RESEARCH – July 2025

The spotlight of the month goes to Andrew Langley et al. at Tufts University, USA, for their impressive work in leveraging photoacoustic imaging for real-time monitoring of phototherapy. Photoacoustic imaging is 3D, non-ionizing and non-invasive imaging method, based on optical absorption that creates pressure waves detected by ultrasound transducer.

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Modulight Spotlights: LASER-SHARP RESEARCH – April 2025

Gokalp et al. from University of Massachusetts and Tufts University constructed an innovative liquid metal nanoparticle platform, which has tumor cell targeting and enhanced encapsulation of verteporfin. Charactierization in vitro with the help of ML6600 laser showed effective in vitro phototoxicity.

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Liquid metal nanoparticles for enhanced delivery of benzoporphyrin derivative in photodynamic cancer therapy

Published in: Photochemistry and Photobiology Authors: Sumeyra Gokalp, Marvin Xavierselvan, Mohammad Forhad Khan, Ronak Shethia, Sima Khani, Ryan H. Riddell, Anna V. Krasnoslobodtseva, Srivalleesha Mallidi, Michelle Foster  

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Power scalable speckle-free multi-wavelength light engine for super-resolution microscopy

Published in: SPIE BIOS 2025 Authors: Anna Essauolva, Sergei Kuehn, Visa Kaivosoja, Andrei Fedotov, Petteri Uusimaa  

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Photodynamic Therapy for Cancer Treatment – Review Article by Nature

Modulight announces a significant contribution to the field of cancer treatment through the publication of a comprehensive review on Photodynamic Therapy (PDT) in Nature Reviews Bioengineering: “Engineering Photodynamics for Treatment, Priming, and Imaging”.

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Fluorescence imaging & endoscopy for tumor visualization and diagnostics

Several fluorescent agents have been approved for fluorescence based diagnosis & intraoperative imaging: Dye generic name Countries Excitation Detection Indications Indocyanine Green (ICG) Worldwide 800 nm Near-infrared (820 nm) Multiple uses: lymphatic mapping, tissue perfusion, visualization of biliary ducts and blood veins, retinal angiography Fluorescein Worldwide 490 nm Green fluorescence (525 nm) Fluorescein angiography or

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Multimodal imaging microscope for tissue engineering applications

  Motivation for the study Tissue engineering is an evolving field of medicine that aims to grow new viable tissue for repairing or regenerating damaged tissues in the body. These tissue constructs are typically made by placing cells in support matrices that have proper growth-inducing factors. However, visualizing the development and composition of these tissue

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ML7710 for fluorescence imaging: Detection of colorectal polyps in humans using c-Met targeted fluorescent peptide

Motivation for the study Polyps are small growths on the inner lining of the colon or rectum, affecting around 1 in 4 people over the age of 50. Certain types of polyps may eventually become cancerous, and colon cancer prevention relies on colonoscopy using white light to detect and remove the polyps. However, small and

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