Tag: fluorescence

Modulight Spotlights: LASER-SHARP RESEARCH – June 2025

Laser-sharp Research / Cancer therapy, fluorescence, in vitro, in vivo, laser-sharp research, liver cancer, ML7710, pancreas, pancreatic cancer, theranostics, University of Maryland

Chen-Hua Ma et al. Optical Therapeutics & Nanotechnology Laboratory at University of Maryland combined photoimmunotherapy with ethanol ablation to achieve improved drug retention and light penetration, especially important for treating pigmented organs like liver and pancreas. Modulight’s ML7710 laser was used for both therapeutic activation of the nanoconstruct, as well as for theranostic monitoring of the process.

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Synergizing photodynamic therapy and ethanol ablation: Light-activatable sustained-exposure ethanol injection technology for enhanced tumor ablation

Scientific papers / Cancer therapy, fluorescence, in vitro, in vivo, liver cancer, ML7710, pancreas, pancreatic cancer, theranostics, University of Maryland

Published in: Bioengineering & Translational Medicine Authors: Chen-Hua Ma, Jeffrey Yang, John A. Quinlan, Kathryn McNaughton, Michele L. Kaluzienski, Tessa Hauser, Matthew F. Starost, Jenna L. Mueller, Huang-Chiao Huang

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Fluorescence-guided photoimmunotherapy for peritoneal carcinomatosis

Scientific papers / carcinomatosis, fluorescence, fluorescence-guided surgery, nanotechnology, ovarian cancer, Photoimmunotherapy

Published in: SPIE BIOS 2024 Authors: Barry Liang, Sumiao Pang, Robert Perttilä, Chen-Hua Ma, Payal Srivastava, Brandon Gaitan, Aaron Sorrin, Nada Fadul, Idrisa Rahman, Zoe Ylöniemi, Dana Roque, Tayyaba Hasan, Petteri Uusimaa, Huang-Chiao Huang

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Pioneering study confirms benefits of Modulight’s technology and photoimmunotherapy for ovarian cancer

Press Releases / fluorescence, medical laser, ML7710, ovarian cancer, Photoimmunotherapy

A study published in Science Advances has for the first time scientifically demonstrated the potential of fluorescence-guided photoimmunotherapy enabled with Modulight’s laser platform and cloud technology. The study, a collaboration between the University of Maryland (UMD) and Modulight, confirms the benefits of targeted nanomedicine, Modulight’s medical laser system, and fluorescence-guided intervention in both achieving better treatment

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Fluorescence endoscopy

application pages / 405 nm, 445 nm, 488 nm, 532 nm, 561 nm, 633 nm, 640 nm, 660 nm, 808 nm, absorbance, dyes, emission, endoscopy, fluorescence, fluorescent dyes, fluorophore

Fluorescence endoscopyFluorescence endoscopy is the latest advancement in endoscopy technology, which uses specialized dyes to highlight specific areas of interest and provide better visibility and image quality during procedures. This technology has revolutionized the way we view the inside of the body, enabling doctors to obtain more detailed images of the gastrointestinal tract, lungs, bladder,

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Fluorescence imaging & endoscopy for tumor visualization and diagnostics

Application Note / 5-ALA, bladder cancer, bronchoscopy, cystoscope, cystoscopy, endoscope, endoscopy, fluorescence, gastroscopy, ICG, imaging, indocyanine green, Lung cancer, ML7710, NIR endoscopy, oncology, RGB

Several fluorescent agents have been approved for fluorescence based diagnosis & intraoperative imaging: Dye generic name Countries Excitation Detection Indications Indocyanine Green (ICG) Worldwide 800 nm Near-infrared (820 nm) Multiple uses: lymphatic mapping, tissue perfusion, visualization of biliary ducts and blood veins, retinal angiography Fluorescein Worldwide 490 nm Green fluorescence (525 nm) Fluorescein angiography or

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Flow cytometry

Application Note / 405nm, 488nm, 532nm, 561nm, 633nm, 640nm, 660nm, 808nm, cell sorting, diagnostics, flow cytometry, fluorescence, ML6600, research

Introduction Flow cytometry is a widely used method in biomedical research and increasingly also in clinical diagnostics. It is a powerful and rapid technique to analyze physical and chemical properties of single cells or particles as they are suspended in liquid and pass in a narrow line across laser beams. Fluorescence together with scattered laser

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