Tag Archives: fluorescence imaging

Modulight Spotlights: LASER-SHARP RESEARCH – August 2022

 Modulight Spotlights: LASER-SHARP RESEARCH – August 2022 Impressive research on head & neck cancer was published by Obaid Lab for molecular imaging and optical nanotherapeutics, at University of Texas, Dallas. The group used Modulight’s ML6500 for a subtherapeutic modulation of tumor microenvironment of H&N. This significantly improved delivery of molecular imaging agent to the tumors as well as improved diagnostic accuracy in detecting tumor tissue by fluorescence. Since incomplete resection and consequent recurrences are common problem with current H&N cancer treatment, this discovery answers unmet Continue reading →

ML7710 for fluorescence imaging: Detection of colorectal polyps in humans using c-Met targeted fluorescent peptide

Motivation for the study Polyps are small growths on the inner lining of the colon or rectum, affecting around 1 in 4 people over the age of 50. Certain types of polyps may eventually become cancerous, and colon cancer prevention relies on colonoscopy using white light to detect and remove the polyps. However, small and flat polyps are difficult to detect and frequently missed with this technique. More precise methods to detect polyps before they progress to colorectal cancer are urgently needed. GE Healthcare’s patented EMI-137 Continue reading →Customer Case Research by: GE Healthcare is a manufacturer and distributor of diagnostic imaging agents and radiopharmaceuticals, R&D collaborations with Leiden University MC for early detection of colorectal tumors. Modulight products: ML7710 series clinical laser system (635 nm, 3 W) Laser use: Clinical single-wavelength laser device used for exciting novel fluorescence probe used to detect colorectal polyps. Link to the study: Dr. James Hardwick, Professor of gastroenterology & hepatology Research topics: Professor Hardwick’s research has contributed to many key improvements in the detection and treatment of colorectal Continue reading →