Tag: customer

ML7710 for photoimmunotherapy against regulatory T cells in tumors

Application Note / cancer, customer, in vivo, Kill cancer, ML7710, Modulight in science, National Cancer Institute, National Institutes of Health, NCI, NIH, oncology, Photoimmunotherapy

Results Tumor growth was significantly suppressed by photoimmunotherapy, compared to control or IgG without light activation. Tumor growth suppression, as well as overall survival after photoimmunotherapy, were significantly better with F(ab´)2 fragments than with full IgG. This efficacy improvement might be related to killer T cells, which were detected in much higher numbers […]

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ML7710 for fluorescence imaging: Detection of colorectal polyps in humans using c-Met targeted fluorescent peptide

Application Note / cancer, clinical, colonoscopy, colorectal cancer, customer, diagnostics, fluorescence detection, fluorescence imaging, GE Healthcare, imaging, Leiden University Medical Center, ML7710, oncology, polyps, targeted agents

Motivation for the study Polyps are small growths on the inner lining of the colon or rectum, affecting around 1 in 4 people over the age of 50. Certain types of polyps may eventually become cancerous, and colon cancer prevention relies on colonoscopy using white light to detect and remove the polyps. However, small and

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Vascular-targeted phototherapy study for prostate cancer

Application Note / customer, in vivo, Memorial Sloan Kettering Cancer Center, ML7710, MSKCC, preclinical, prostate cancer, Weizmann Institute of Science

Study protocol Related Modulight products and Services ML7710 – Laser device suited for pre-clinical and clinical applications » Related Publications WST11 Vascular Targeted Photodynamic Therapy Effect Monitoring by Multispectral Optoacoustic Tomography (MSOT) in Mice Volker Neuschmelting, Kwanghee Kim, Jaber Malekzadeh-Najafabadi, Sylvia Jebiwott, Jaya Prakash, Avigdor Scherz, Jonathan A Coleman, Moritz F Kircher, Vasilis Ntziachristos Theranostics, 2018,

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