Tag Archives: colon cancer

Intratumoral interleukin-15 improves efficacy of near-infrared photoimmunotherapy

July 18, 2023 by Modulight
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Published in: Molecular Cancer Therapeutics Authors: Hiroshi Fukushima, Aki Furusawa, Takuya Kato, Hiroaki Wakiyama, Seiichiro Takao, Shuhei Okuyama, Peter L. Choyke, Hisataka Kobayashi    Published in: Molecular Cancer Therapeutics Authors: Hiroshi Fukushima, Aki Furusawa, Takuya Kato, Hiroaki Wakiyama, Seiichiro Takao, Shuhei Okuyama, Peter L. Choyke, Hisataka Kobayashi   Interleukin 15 (IL-15) is inducer of differentiation and proliferation of CD8+ T cells and NK cells and thus promising candidate for cancer immunotherapy. This study showed therapeutic efficacy increase in vivo when IL15 was combined with cancer cell-targeted photoimmunotherapy using ML7710 laser system. Intratumoral injection of IL-15 was more effective than intraperitoneal in suppressing tumor growth and inducing intratumoral immune responses, Continue reading →

Modulight Spotlights: LASER-SHARP RESEARCH – July 2021

August 4, 2021 by Modulight Content
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 Modulight Spotlights: LASER-SHARP RESEARCH – July 2021 Congratulations for Gina Manda and her team at Victor Babes National Institute of Pathology! Their genetic study unveiled a network of stress responses in tumor cells triggered by PDT. These results expand knowledge of different mechanisms behind therapy-induced cell death and treatment resistance. Read original publication   Modulight is very happy to be supporting this research. We would like to deliver our warmest congratulations to the research team!   #LaserSharpResearch  #ModulightInScience   #LasersInScience #KillCancer  #ColonCancer #Genetics     Continue reading →