Tag Archives: cancer treatment

Modulight Spotlights: LASER-SHARP RESEARCH – October 2024

October 24, 2024 by Modulight Content
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Modulight Spotlights: LASER-SHARP RESEARCH – October 2024 This month, we are highlighting new findings published in RSC Materials Advances by Olga Lem, Roosa Kekki and researchers at Pharmaceutical Nanotechnology research group and Tampere University. The study provides key insights into the role of lipid oxidation in cargo release from light-activated liposomes. These spherical lipid vesicles can be controlled by light to provide time- and site-specific drug delivery, for example for cancer treatment. Red light provides a non-invasive, selective, and safe trigger for releasing liposomal cargo. Modulight’s Continue reading →

Modulight Spotlights: LASER-SHARP RESEARCH – September 2024

September 23, 2024 by Modulight Content
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 Modulight Spotlights: LASER-SHARP RESEARCH – September 2024 University of Maryland and Modulight have published together a new research study about the mechanisms of cancer drug resistance. Drug resistance is a leading cause of treatment failure and often has dramatic consequences for survival of cancer patients. Cancer cells have developed various ways to protect themselves from drugs. When several clinically used photoactive drugs were studied, it was shown that some of them were being actively pumped out by cancer cells, thus likely limiting the full therapeutic potential Continue reading →

Screening of photosensitizers-ATP binding cassette (ABC) transporter interactions in vitro

September 20, 2024 by Modulight Content
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Published in: Cancer Drug Resistance Authors: Shruti Vig1, Payal Srivastava1,#, Idrisa Rahman1,2,#, Renee Jaranson1, Anika Dasgupta1, Robert Perttilä3, Petteri Uusimaa3, Huang-Chiao Huang1  Published in: Cancer Drug Resistance Authors: Shruti Vig1, Payal Srivastava1,#, Idrisa Rahman1,2,#, Renee Jaranson1, Anika Dasgupta1, Robert Perttilä3, Petteri Uusimaa3, Huang-Chiao Huang1 University of Maryland and Modulight have published together a new research study about the mechanisms of cancer drug resistance. Drug resistance is a leading cause of treatment failure and often has dramatic consequences for survival of cancer patients. Cancer cells have developed various ways to protect themselves from drugs. When several clinically used photoactive drugs were studied, it was shown that some of them were being actively pumped out by cancer cells, thus likely limiting the full therapeutic potential of these Continue reading →

ML7710 for photoactivated treatment of lung cancer

March 6, 2024 by Modulight Content
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Deadliest cancer Precision with photoactivation Photoimmunotherapy with ML7710 offers a clinical therapeutic option for NSCLC patients even with advanced disease stage. Besides laser light, this therapy involves photoactivated drug, which can be activated precisely at the tumor site with laser fibers, hence minimizing drug effects to healthy tissues. Smaller invasiveness compared to surgery can enable patients to stay less time recovering at the hospital. It can also be repeated if needed multiple times without cumulating toxicities, unlike radiation therapy. Some previously inoperable tumors can decrease Continue reading →Deadliest cancer Lung cancer is the leading cause of cancer deaths worldwide, with more than 2.2 million cases and 1.8 million deaths each year [1]. Lung cancer can be divided into two types, small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), with the latter accounting for about 85% of all lung cancer cases. NSCL is usually less sensitive to chemo- and radiotherapy and in many cases tumor cannot be removed surgically or has spread from lungs to distant sites at the time Continue reading →

Cloud-based medical laser platform for phototherapy and treatment monitoring for glioblastoma

March 5, 2021 by Modulight Content
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Presented in: SPIE BIOS 2021 Authors: Zoe Ylöniemi, Visa Kaivosoja, Juha Lemmetti, Timo Tanila, Eero Koivumäki, Lasse Orsila, Petteri Uusimaa    Presented in: SPIE BIOS 2021 Authors: Zoe Ylöniemi, Visa Kaivosoja, Juha Lemmetti, Timo Tanila, Eero Koivumäki, Lasse Orsila, Petteri Uusimaa Photodynamic therapy is a cancer treatment modality with great potential but moderate clinical success. One reason for the sub-optimal clinical success is the limited knowledge about light distribution in tissues and lack of ways to monitor treatment real-time. Modulight has developed a laser platform for glioblastoma which will utilize real-time treatment monitoring based on spectral properties of the tissue and the drug. This therapy modality is based on photodynamic therapy with Continue reading →

Oncology

June 24, 2014 by Modulight
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[slideshow_deploy id=’488′] Oncology Modulight laser systems are ideal solution for oncology, surgery & bacteria removal (photo disinfection). In Photodynamic therapy (PDT) alone – tens of hospitals use our systems. Our ML7710 is the most configurable laser platform in the world and boasts a unique platform approval. It boasts up to 8 channels, multiple wavelengths, tens of Watts optical power from 400 to 2000nm. All platform certification to accelerate your product development or clinical trials. Our systems boast unparalleled flexibility and ease-of-use. Produts are supported with Continue reading →[slideshow_deploy id='488'] Oncology Modulight laser systems are ideal solution for oncology, surgery & bacteria removal (photo disinfection). In Photodynamic therapy (PDT) alone – tens of hospitals use our systems. Our ML7710 is the most configurable laser platform in the world and boasts a unique platform approval. It boasts up to 8 channels, multiple wavelengths, tens of Watts optical power from 400 to 2000nm. All platform certification to accelerate your product development or clinical trials. Our systems boast unparalleled flexibility and ease-of-use. Produts are supported with Continue reading →