Tag: breast cancer

Modulight Spotlights: LASER-SHARP RESEARCH – February 2025

A. Lepland and the teams at University of Tartu, Estonia and Veneto Institute of Oncology, Italy, developed a new immunotherapy for triple negative breast cancer, using Modulight ML6000-series laser. Tumor growth slowed down and the cancer’s spreading to the lungs was suppressed.

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Comparative study of immune response to local tumor destruction modalities in a murine breast cancer model

Scientific papers / 755 nm, breast cancer, immunotherapy, in vivo, Memorial Sloan Kettering Cancer Center, ML7710, PDT, T cells, Tookad, tumor, vascular-targeted PDT

Published in: Frontiers in Oncology Authors: Sadna Budhu, Kwanghee Kim, Wesley Yip, Stephen La Rosa, Sylvia Jebiwott, Liqun Cai, Aliya Holland, Jasmine Thomas, Dina Preise, Alex Somma, Benjamin Gordon, Avigdor Scherz, Jedd D. Wolchok, Joseph Erinjeri, Taha Merghoub, Jonathan A. Coleman

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A Non-Invasive Deep Photoablation Technique to Inhibit DCIS Progression and Induce Antitumor Immunity

Scientific papers / 690 nm, breast cancer, in vitro, in vivo, ML7710, ML8500, PDT

Published in: Cancers Authors: Kensuke Kaneko, Hiroshi Nagata, Xiao-Yi Yang, Joshua Ginzel, Zachary Hartman, Jeffrey Everitt, Philip Hughes, Timothy Haystead, Michael Morse, Herbert Kim Lyerly, Takuya Osada

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Combination of a novel heat shock protein 90-targeted photodynamic therapy with PD-1/PD-L1 blockade induces potent systemic antitumor efficacy and abscopal effect against breast cancers

Scientific papers / breast cancer, HeatShockProtein, HSP90, immunecheckpoints, in vitro, in vivo, ML7710, PDT

Published in: Journal for ImmunoTherapy of Cancer Authors: Kensuke Kaneko, Chaitanya R Acharya, Hiroshi Nagata, Xiao Yang, Zachary Conrad Hartman, Amy Hobeika, Philip F Hughes, Timothy A J Haystead, Michael A Morse, Herbert Kim Lyerly, Takuya Osada

Combination of a novel heat shock protein 90-targeted photodynamic therapy with PD-1/PD-L1 blockade induces potent systemic antitumor efficacy and abscopal effect against breast cancers Read More »

Development of heat shock protein 90-targeted PDT for inflammatory breast cancer

Application Note / 665 nm, 689 nm, 750 nm, breast cancer, Duke University, HS201, HSP90, in vitro, in vivo, ML7710, ML8500, verteporfin

Motivation of the study In photodynamic therapy (PDT), systemically administered photosensitizer is activated within the tumor using focused near-infrared light, typically a laser with a wavelength matching the absorption peak of the photosensitizer. Several photosensitizers have been clinically approved for the treatment of different cancers; however, their accumulation is non-tumor exclusive which exposes healthy tissues

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Theranostic Prospects of Graphene Quantum Dots in Breast Cancer

Scientific papers / breast cancer, cancer, ML7710, nanotechnology, Photodynamic therapy, photothermal therapy

Published in: ACS Biomaterials Science and Engineering Authors: Rahul S. Tade, Pravin O. Patil

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Heat shock protein 90-targeted photodynamic therapy enables treatment of subcutaneous and visceral tumors

Scientific papers / 690 nm, breast cancer, HSP90, in vitro, ML7710, ML8500, PDT, Photodynamic therapy, preclinical, targeted therapies, verteporfin

Published in: Communications Biology Authors: Kensuke Kaneko, Takuya Osada, Michael A. Morse, William R. Gwin, Joshua D. Ginzel, Joshua C. Snyder, Xiao-Yi Yang, Cong-Xiao Liu, Márcio A. Diniz, Khaldon Bodoor, Philip F. Hughes, Timothy AJ. Haystead, H. Kim Lyerly

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Fully automated illumination study series for modern cancer drug development

Application Note / breast cancer, drug development, drug discovery, in vitro, ML7710, ML8500, Roswell Park Cancer Institute, University of Sao Paulo

Fully automated illumination study series for modern cancer drug development In vitro cell viability and dose escalation study for developing photosensitive or photoactivated drugs using Modulight ML7710 medical laser and ML8500 automated illumination system. Experimental set up

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