Photoimmunotherapy

Modulight Spotlights: LASER-SHARP RESEARCH – April 2025

Gokalp et al. from University of Massachusetts and Tufts University constructed an innovative liquid metal nanoparticle platform, which has tumor cell targeting and enhanced encapsulation of verteporfin. Charactierization in vitro with the help of ML6600 laser showed effective in vitro phototoxicity.

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Impact of Vitamin C on Immune Response and Edema Following Near-Infrared Photoimmunotherapy (NIR-PIT)

Published in: Cancer Science Authors: Hiroshi Yamamoto, Aki Furusawa, Hiroshi Fukushima, Seiichiro Takao, Motofumi Suzuki, Makoto Kano, Miyu Kano, Shuhei Okuyama, Ko Kitamura, Peter L. Choyke, Hisataka Kobayashi  

Impact of Vitamin C on Immune Response and Edema Following Near-Infrared Photoimmunotherapy (NIR-PIT) Read More »

Carbonic anhydrase-9-targeted near-infrared photoimmunotherapy as a theranostic modality for clear cell renal cell carcinoma

Published in: International Journal of Cancer Authors: Hiroshi Fukushima, Seiichiro Takao, Aki Furusawa, Motofumi Suzuki, Youfeng Yang, Christopher J. Ricketts, Makoto Kano, Shuhei Okuyama, Hiroshi Yamamoto, Miyu Kano, Mark W. Ball, Peter L. Choyke, W. Marston Linehan, Hisataka Kobayashi  

Carbonic anhydrase-9-targeted near-infrared photoimmunotherapy as a theranostic modality for clear cell renal cell carcinoma Read More »

Tissue factor targeted near‑infrared photoimmunotherapy: a versatile therapeutic approach for malignancies

Published in: Cancer Immunology, Immunotherapy Authors: Seiichiro Takao, Hiroshi Fukushima, Aki Furusawa, Takuya Kato, Shuhei Okuyama, Makoto Kano, Hiroshi Yamamoto, Motofumi Suzuki, Miyu Kano, Peter L. Choyke, Hisataka Kobayashi  

Tissue factor targeted near‑infrared photoimmunotherapy: a versatile therapeutic approach for malignancies Read More »

Modulight Spotlights: LASER-SHARP RESEARCH – August 2024

Hirofumi Hanaoka and the team at Kansai Medical University, Japan developed a new laser fiber and method for illumination of narrow cavities, such as esophagus. The new fiber together with ML7710 laser allowed better illumination of the entire tumor compared to existing fibers, resulting in tumor growth suppression.

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Near‐infrared photoimmunotherapy targeting PD‐L1: Improved efficacy by preconditioning the tumor microenvironment

Published in: Cancer Science Authors: Fuyuki F. Inagaki, Makoto Kano, Aki Furusawa, Takuya Kato, Ryuhei Okada, Hiroshi Fukushima, Seiichiro Takao, Shuhei Okuyama, Peter L. Choyke, Hisataka Kobayashi  

Near‐infrared photoimmunotherapy targeting PD‐L1: Improved efficacy by preconditioning the tumor microenvironment Read More »

Phototruncation cell tracking with near-infrared photoimmunotherapy using heptamethine cyanine dye to visualise migratory dynamics of immune cells

Published in: eBioMedicine Authors: Hiroshi Fukushima, Aki Furusawa, Seiichiro Takao, Siddharth S. Matikonda, Makoto Kano, Shuhei Okuyama, Hiroshi Yamamoto, Peter L. Choyke, Martin J. Schnermann, Hisataka Kobayashi  

Phototruncation cell tracking with near-infrared photoimmunotherapy using heptamethine cyanine dye to visualise migratory dynamics of immune cells Read More »

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