Kill cancer

Modulight Spotlights: LASER-SHARP RESEARCH – August 2024

Hirofumi Hanaoka and the team at Kansai Medical University, Japan developed a new laser fiber and method for illumination of narrow cavities, such as esophagus. The new fiber together with ML7710 laser allowed better illumination of the entire tumor compared to existing fibers, resulting in tumor growth suppression.

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Modulight Spotlights: LASER-SHARP RESEARCH – July 2024

New findings in prostate cancer research were reported by Xinning Wang and team at Case Western University, Comprehensive Cancer Center. Using ML7710 laser at 672 nm for activation of the drug, they were able to dramatically improve therapeutic effect in prostate cancer models.

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Modulight Spotlights: LASER-SHARP RESEARCH – June 2021

Modulight Spotlights: LASER-SHARP RESEARCH – June 2021 The findings by Prof. Lothar Lilge and his team might enable improved treatment of diffuse lung metastasis which are difficult to treat with standard therapies. A novel lung perfusion platform significantly reduced tissue absorption and allowed better light penetration, resulting in up to 3-fold increased treatment volumes.  

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ML7710 for photoimmunotherapy against regulatory T cells in tumors

    Results Tumor growth was significantly suppressed by photoimmunotherapy, compared to control or IgG without light activation. Tumor growth suppression, as well as overall survival after photoimmunotherapy, were significantly better with F(ab´)2 fragments than with full IgG. This efficacy improvement might be related to killer T cells, which were detected in much higher numbers

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Modulight Spotlights: LASER-SHARP RESEARCH – May 2021

Modulight Spotlights: LASER-SHARP RESEARCH – May 2021 The renowned pioneer in photoimmunotherapy (PIT), Professor Hisataka Kobayashi, has published an outstanding article with his team at National Cancer Institute / NIH. The article is about improving the antitumor efficacy of near-infrared photoimmunotherapy (NIR-PIT) by simultaneous targeting of cancer cells and regulatory T cells in the tumor

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Modulight Spotlights: LASER-SHARP RESEARCH – April 2021

Modulight Spotlights: LASER-SHARP RESEARCH – April 2021 Dr. Rhonda Kines and the team at Aura Biosciences reported promising results of their VLP (virus-like particle) photosensitizer-conjugate eliciting strong and long-lasting anti-tumor immune responses, as well as potential to combine this agent with immune checkpoint inhibitors for even improved antitumor efficacy. Read original publication   Modulight is

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