Tag Archives: 690nm

Modulight Spotlights: LASER-SHARP RESEARCH – November 2021

     Modulight Spotlights: LASER-SHARP RESEARCH – November 2021 Dr. Aaron Sorrin and researchers at the University of Maryland found a new potential combination therapy for ovarian cancer. This combination includes a novel light-based technology, called photodynamic priming, and a targeted therapeutic against a specific cancer cell receptor, effectively suppressing invasion of cancer cells. Modulight’s scientific board wanted to highlight this research especially because novel therapeutic solutions are urgently needed against this aggressive disease, which despite the best possible current therapies, recurs in most patients leading to Continue reading →

Nanobody-targeted photodynamic therapy for the treatment of feline oral carcinoma: a step towards translation to the veterinary clinic

Published in: Nanophotonics Authors: Irati Beltrán Hernández, Guillaume C.M. Grinwis, Alessia Di Maggio, Paul M.P. van Bergen en Henegouwen, Wim E. Hennink, Erik Teske, Jan W. Hesselink, Sebastiaan A. van Nimwegen, Jan A. Mol, Sabrina Oliveira    Published in: Nanophotonics Authors: Irati Beltrán Hernández, Guillaume C.M. Grinwis, Alessia Di Maggio, Paul M.P. van Bergen en Henegouwen, Wim E. Hennink, Erik Teske, Jan W. Hesselink, Sebastiaan A. van Nimwegen, Jan A. Mol, Sabrina Oliveira   Nanobody-targeted PDT was shown in vitro to be suitable and efficient for oral carcinoma, which expresses EGFR. Modulight laser was used as an illumination source to activate PDT. Next aim is to treat cats with oral carcinoma before advancing to human clinic.   Read the article here

Virus-like particle-drug conjugates induce protective, long-lasting adaptive anti-tumor immunity in the absence of specifically targeted tumor antigens

Published in: Cancer Immunology Research Authors: Rhonda C Kines, Cynthia D Thompson, Sean Spring, Zhenyu Li, Elisabet de los Pinos, Stephen Monks, John T Schiller       Related application note: Vision-sparing targeted phototherapy for uveal melanoma  Published in: Cancer Immunology Research Authors: Rhonda C Kines, Cynthia D Thompson, Sean Spring, Zhenyu Li, Elisabet de los Pinos, Stephen Monks, John T Schiller   This study examined the ability of a papillomavirus-like particle drug-conjugate (AU-011) to eradicate subcutaneous tumors after intravenous injection and to subsequently elicit long-term anti-tumor immunity in the TC-1 syngeneic murine tumor model. Also the combination of AU-011 with immune checkpoint inhibitor antibodies (anti-CTLA-4 or anti-PD-1) was studied and improved therapeutic efficacy. Modulight laser + MLAKIT was used only for Continue reading →

Modulight introduces high-power TO-can red lasers

Tampere, Finland, November 1st, 2007 – Modulight’s hot-red ChiliLase family gladly welcomes its new generation of lasers: the TO-can, single-emitter red lasers. Modulight’s new laser release includes 3 different products: ML1468 – 635 nm, 200 mW in a 9 mm TO-can ML1504 – 635 nm, 500 mW in a 9 mm TO-can ML1469 – 690 nm, 350 mW in a 9 mm TO-can These high performance laser products are designed for use in applications requiring high optical power from a small emitter area and a Continue reading →