630 nm

Comprehensive reanalysis of light fluence distribution in pleural photodynamic therapy using standardized anatomical coordinates

Published in: Photochemistry and Photobiology Authors: Hongjing Sun, Michele M. Kim, Yi Hong Ong, Andreea Dimofte, Sunil Singhal, Theresa M. Busch, Keith A. Cengel, Timothy C. Zhu  

Comprehensive reanalysis of light fluence distribution in pleural photodynamic therapy using standardized anatomical coordinates Read More »

Introducing Modulight’s Versatile DBR Laser platform

Introducing Modulight’s Versatile DBR Laser platform Modulight announces the launch of its latest Distributed Bragg Reflector (DBR) lasers, offering a configurable wavelength range from 630 nm to 1100 nm. These advanced lasers are designed to meet the high demands in quantum systems, quantum sensing, Raman spectroscopy, and metrology.  Key wavelengths of Modulight DBR laser platform

Introducing Modulight’s Versatile DBR Laser platform Read More »

Ru(II) Oligothienyl Complexes with Fluorinated Ligands: Photophysical, Electrochemical, and Photobiological Properties

Published in: Inorganic Chemistry Authors: Houston D. Cole, Abbas Vali, John A. Roque III, Ge Shi, Alisher Talgatov, Gurleen Kaur, Antonio Francés-Monerris, Marta E. Alberto, Colin G. Cameron, Sherri A. McFarland  

Ru(II) Oligothienyl Complexes with Fluorinated Ligands: Photophysical, Electrochemical, and Photobiological Properties Read More »

ML7710 for photoactivated treatment of lung cancer

Deadliest cancer Precision with photoactivation Photoimmunotherapy with ML7710 offers a clinical therapeutic option for NSCLC patients even with advanced disease stage. Besides laser light, this therapy involves photoactivated drug, which can be activated precisely at the tumor site with laser fibers, hence minimizing drug effects to healthy tissues. Smaller invasiveness compared to surgery can enable

ML7710 for photoactivated treatment of lung cancer Read More »

Optimizing photosensitizer administration for cancer therapy

  Motivation While Photofrin PDT is an approved oncological therapy for multiple indications, its wider use is hindered by prolonged skin photosensitivity lasting several weeks. The aim of this study is to investigate intratumoral Photofrin administration as a way to decrease skin photosensitivity compared to the standard IV injection protocol. Tumor necrosis after PDT was

Optimizing photosensitizer administration for cancer therapy Read More »

Light delivery optimization for H&N cancer treatment

Results Illumination with one fiber Some level of tissue heating was observed at all used light intensities. At lower intensities (60-100 mW/cm), less than 5% of the tumor was subjected to >60 ⁰C temperature, a point where irreversible thermal damage will immediately occur (photothermal ablation). At intensities of 150-200 mW/cm, 15-20% of the tumor was

Light delivery optimization for H&N cancer treatment Read More »

Irradiance controls photodynamic efficacy and tissue heating in experimental tumours: implication for interstitial PDT of locally advanced cancer

Published in: British Journal of Cancer Authors: Gal Shafirstein, David A. Bellnier, Emily Oakley, Sasheen Hamilton, Michael Habitzruther, Lawrence Tworek, Alan Hutson, Joseph A. Spernyak, Sandra Sexton, Leslie Curtin, Steven G. Turowski, Hassan Arshad, Barbara Henderson    

Irradiance controls photodynamic efficacy and tissue heating in experimental tumours: implication for interstitial PDT of locally advanced cancer Read More »

Scroll to Top