Tag: 5-ALA

Modulight Spotlights: LASER-SHARP RESEARCH – November 2024

Laser-sharp Research / Modulight Content / 5-ALA, colorectal cancer, illumination, in vivo, laser-sharp research, light activation, Lung cancer, ML6600, noveltherapies, perfusion, Photodynamic therapy

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Carrier-Free, Amorphous Verteporfin Nanodrug for Enhanced Photodynamic Cancer Therapy and Brain Drug Delivery

Scientific papers / Modulight Content / 5-ALA, blood-brain-barrier, brain cancer, drug delivery, glioblastoma, MLACAL, Modulight in science, PDT, Photodynamic therapy, photosensitizer, research

Published in: Advanced Science Authors: John A. Quinlan, Collin T. Inglut, Payal Srivastava, Idrisa Rahman, Jillian Stabile, Brandon Gaitan, Carla Arnau Del Valle, Kaylin Baumiller, Anandita Gaur, Wen-An Chiou, Baktiar

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Fluorescence imaging & endoscopy for tumor visualization and diagnostics

Application Note / Modulight Content / 5-ALA, bladder cancer, bronchoscopy, cystoscope, cystoscopy, endoscope, endoscopy, fluorescence, gastroscopy, ICG, imaging, indocyanine green, Lung cancer, ML7710, NIR endoscopy, oncology, RGB

Several fluorescent agents have been approved for fluorescence based diagnosis & intraoperative imaging: Dye generic name Countries Excitation Detection Indications

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Light penetration depth in brain with different photosensitizers

Application Note / Modulight Content / 5-ALA, 635 nm, 689 nm, BPD, brain cancer, glioblastoma, ML6600, PDT, Photoimmunotherapy, PIT, PPIX, University of Maryland, verteporfin

Motivation for the study Glioblastoma is the most aggressive and lethal brain cancer with an average prognosis of 15

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ML7710 for glioblastoma treatment

Application Note / Modulight Content / 5-ALA, brain cancer, fluorescence-guided surgery, glioblastoma, ML7710, PDT, Photodynamic therapy, PPIX, reactive oxygen species, UKM, University Hospital Münster

Background Professor Stummer on glioblastoma surgeries and iPDT: Treatment protocol 20 patients were treated. 5-ALA (Gliolan) was administered

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Cloud-based medical laser platform for phototherapy and treatment monitoring for glioblastoma

Scientific papers / Modulight Content / 5-ALA, 635 nm, AI, cancer treatment, fluorescence, glioblastoma, PDT, Photodynamic therapy, PPIX, treatment monitoring

Presented in: SPIE BIOS 2021 Authors: Zoe Ylöniemi, Visa Kaivosoja, Juha Lemmetti, Timo Tanila, Eero Koivumäki, Lasse Orsila, Petteri Uusimaa

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Configurable cloud based medical laser platform with real-time treatment monitoring

Scientific papers / Modulight Content / 5-ALA, AI, BIOS, cloud-connected, illumination, laser platform, ML7710, nanoparticle, photosensitizer, tumor

Presented in: SPIE BIOS 2021 Authors: Visa Kaivosoja, Zoe Ylöniemi, Juha Lemmetti, Timo Tanila, Lasse Orsila, Petteri Uusimaa, Modulight, Inc.

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Combination of ALA-induced fluorescence-guided resection and intraoperative open photodynamic therapy for recurrent glioblastoma: case series on a promising dual strategy for local tumor control

Scientific papers / Modulight Content / 5-ALA, clinical, compassionate care, FGR, Fluorescence-guided resection, glioblastoma, ML7710, PDT, PPIX

Published in: Journal of Neurosurgery Authors: Stephanie Schipmann, Michael Müther, Louise Stögbauer, Sebastian Zimmer, Benjamin Brokinkel, Markus Holling, Oliver Grauer,

Combination of ALA-induced fluorescence-guided resection and intraoperative open photodynamic therapy for recurrent glioblastoma: case series on a promising dual strategy for local tumor control Read More »