Tag: 488 nm

Robust and field-replaceable multiwavelength laser system for flow cytometry

Flow cytometry requires stable, precisely-shaped laser light for accurate fluorescence detection. Modulight’s ML6640 laser engine integrates automatic beam alignment and built-in beam shaping to deliver stable, uniform illumination over time. This work presents updated characterization results of the ML6640, including beam uniformity, optical stability, and alignment performance.

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Improving efficiency and stability of power-scalable light engine for super-resolution microscopy

Scientific papers / 355 nm, 405 nm, 488 nm, 532 nm, 561 nm, 638 nm. lowe speckle, BIOS, flat-top beam profile, fluorophores, low-noise, ML6600, multi-color imaging, SPIE, SRM, super-resolution microscopy / March 5, 2026

This paper presents recent enhancements to Modulight’s power-scalable light engine for super-resolution microscopy, improving power stability, dynamic range, and overall robustness to meet the demanding requirements of advanced biological imaging applications.

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ML6600 laser engine for DNA and RNA sequencing

Next-Generation Sequencing

Application Note / 488 nm, 535 nm, 594 nm, 640 nm, 660 nm, Dequencing optics, DNA, DNA sequencing, fluorescence detection, high-throughput sequencing, laser engine, ML6600, multi-wavelength lasers, NGS, nucleotides, SBS sequencing, sequencing, sequencing illumination / February 11, 2026

Learn how Modulight’s ML6600 laser engine enhances DNA and RNA sequencing accuracy with stable multi-wavelength illumination, precision optics, and fully integrated design for next-generation sequencing systems. Modulight’s in-house laser platform delivers all key excitation wavelengths, including 532 nm (green), 640—660 nm (red), 780—790 nm (IR), and 570—630 nm (yellow-orange).

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Modulight Introduces High-Power Yellow and Orange Lasers to Bridge the “Yellow-Orange Gap”

Press Releases / 488 nm, 493 nm, 532 nm, 561 nm, 570 nm, 572 nm, 577 nm, 578 nm, 589 nm, 614 nm, 615 nm, 630 nm, astronomy, coagulation, dermatology, flow cytometry, genomics, light projection, medical, microscopy, ML6600, ophthalmology, orange, quantum computing, quantum sensing, usability, VECSEL, Yellow, yellow-orange-gap / January 20, 2026

Modulight announces yellow and orange laser wavelengths with several watts of output power, excellent beam quality, and unmatched flexibility. Traditionally difficult to achieve, Modulight’s VECSEL-based ML6600 series lasers now close the yellow-orange gap between 570 and 630 nm.

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Power scalable speckle-free multi-wavelength light engine for super-resolution microscopy

Scientific papers / 355 nm, 405 nm, 488 nm, 561 nm, 638 nm, BIOS, imaging, laser engine, microscopy, ML6600, Modulight authors, narrow linewidth, Photonics West, speckle removal, SPIE, super-resolution microscopy / March 19, 2025

Published in: SPIE BIOS 2025 Authors: Anna Essauolva, Sergei Kuehn, Visa Kaivosoja, Andrei Fedotov, Petteri Uusimaa The microscopy field has been rapidly developing lately, focusing on enhancing resolution, speed, and versatility within the imaging methods. Among several rapidly developing microscopy techniques is super-resolution microscopy, which enables surpassing of the diffraction limit of light and, thus, gives us access to

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ML6600 Expands with VECSEL-Based Variants for Flow Cytometry

Press Releases / 349 nm, 488 nm, 561 nm, flow cytometry, laser technologies, ML6600, ML6640, OP-VECSEL, tailored lasers, VECSEL / January 17, 2025

Advancing Flow Cytometry Precision with VECSEL-Based Flow Cytometry Lasers Modulight expands its ML6600 product family with new high-performance flow cytometry lasers designed to meet the rigorous demands of cell analysis and sorting. Featuring Modulight’s OP-VECSEL (Optically-Pumped Vertical-External-Cavity Surface-Emitting Laser) core technology, these latest ML6600 variants offer unparalleled stability, beam quality, and efficiency for biomedical research

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Modulight Introduces ML6640: The Next Evolution in Flow Cytometry Laser Technology

Press Releases / 405 nm, 488 nm, 561 nm, 638 nm, cell sorting, flow cytometry, ML6600, ML6640 / January 17, 2025

Modulight ML6640 is designed for flow cytometry and cell sorting applications. This advanced laser engine incorporates four precisely selected wavelengths: 405 nm, 488 nm, 561 nm, and 638 nm (for other wavelengths contact factory). It’s optimized for fluorochrome excitation, including PE (Phycoerythrin)-based dyes critical for multi-parameter analysis.

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ML6600-based Laser Solutions for Microscopy

Press Releases / 405 nm, 488 nm, 561 nm, 638 nm, illumination, microscopy, ML6600, super-resolution microscopy / January 2, 2025

Modulight proudly announces new variants of its ML6600 platform, designed specifically for the demanding requirements of microscopy illumination, such as super-resolution microscopy. These advanced solutions support both single-wavelength and multi-wavelength configurations, tailored to meet diverse customer needs in imaging applications. ML6600 platform provides all key wavelengths for microscopy—for example 355nm, 405 nm, 488 nm, 532nm, 561 nm, and 638 nm.

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Fluorescence endoscopy

application pages / 405 nm, 445 nm, 488 nm, 532 nm, 561 nm, 633 nm, 640 nm, 660 nm, 808 nm, absorbance, dyes, emission, endoscopy, fluorescence, fluorescent dyes, fluorophore / June 23, 2023

Fluorescence endoscopyFluorescence endoscopy is the latest advancement in endoscopy technology, which uses specialized dyes to highlight specific areas of interest and provide better visibility and image quality during procedures. This technology has revolutionized the way we view the inside of the body, enabling doctors to obtain more detailed images of the gastrointestinal tract, lungs, bladder,

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