The review article, titled “Engineering Photodynamics for Treatment, Priming, and Imaging”, explores the advanced applications of PDT, a photochemistry-based treatment approach that utilizes light-activated photosensitizers to generate reactive oxygen species for localized cellular cytotoxicity. The paper discusses the underlying mechanisms of PDT and photodynamic priming (PDP), their roles in cancer treatment, and the engineering of photosensitizers for enhanced efficacy and specificity.
“Having a review article in Nature is a significant achievement for the entire PDT field, benefiting research teams, cancer centers, and the industry as a whole. This recognition underscores the collaborative effort and dedication of all involved in advancing this promising cancer therapy. Modulight is proud to contribute to advancements in PDT, offering cutting-edge solutions to enhance the efficacy and precision of cancer treatments. Together, we’re making strides towards a future where cancer is a thing of the past,” said Dr. Petteri Uusimaa, CTO of Modulight.
Authors of the Review Article:
- Girgis Obaid, University of Texas at Dallas
- Jonathan P. Celli, University of Massachusetts Boston
- Mans Broekgaarden, Grenoble Alpes University
- Anne-Laure Bulin, Grenoble Alpes University
- Petteri Uusimaa, Modulight Corporation
- Brian Pogue, University of Wisconsin School of Medicine
- Tayyaba Hasan, Harvard Medical School
- Huang-Chiao Huang, University of Maryland