Fast quantitative ROS detection based on dual-color single rare-earth nanoparticle imaging reveals signaling pathway kinetics in living cells

Published in: Nanoscale

Authors: M. Abdesselem, R. Ramodiharilafy, L. Devys, T. Gacoin, A. Alexandrou, C. I. Bouzigues


Reactive oxygen species (ROS), and notably hydrogen peroxide H2O2, are cellular second messengers that are known to control a variety of signaling processes.  Modulight ML6600 series laser was used to excite colloidal nanoparticles for luminescence measurements as part of a rapid ROS detection probe. The probe was used to study signaling pathway kinetics in living cells.


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