Published in: Photochemistry and Photobiology
Authors: Hongjing Sun, Michele M. Kim, Yi Hong Ong, Andreea Dimofte, Sunil Singhal, Theresa M. Busch, Keith A. Cengel, Timothy C. Zhu
Accurate light dosimetry during PDT is crucial for treatment efficacy. The study presents an improved method for analyzing light fluence distribution in pleural PDT using a standardized anatomical coordinate system and advanced computational modeling. An infrared navigation system was used together with an improved treatment wand to track light delivery in real-time. The coordinate system allowed direct comparison across patients and showed acceptable light fluence uniformity with standard deviation of 6.6% in 11 patients. ML7710 was used as a light source for PDT.
