We are delighted to highlight new exciting study by Rahman et al. from Dr. Huang-Chiao Huang’s lab at University of Maryland. Multidrug resistance remains a significant barrier to successful chemotherapy outcomes for cancer patients, often caused by active pumping of chemotherapeutics outside of cancer cells. Hence, the team studied four different formulations of verteporfin for their ability to inhibit a key receptor associated with multidrug resistance, using ML8500 laser system together with Seahorse assay. Impressively, a formulation called nanoVP, a promising new formulation for glioblastoma, was able to overcome resistance when activated with sub-lethal light dose. This highlights its potential in sensitizing resistant tumors to chemotherapy via photoactivation-based modulation.

Modulight is very happy to be supporting this research. We would like to deliver our warmest congratulations to the research team!

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About Modulight’s LASER-SHARP RESEARCH concept:

Laser-Sharp Research is a concept where our scientific board highlights cutting-edge scientific research articles from our customers. Important selection criteria are that Modulight and laser product are mentioned in the publication, the impact and relevance of the results, clinical translatability, as well as scientific quality of the journal. The nominated research groups will be rewarded to encourage the great work done.