University of Maryland and Modulight have published together a new research study about the mechanisms of cancer drug resistance. Drug resistance is a leading cause of treatment failure and often has dramatic consequences for survival of cancer patients. Cancer cells have developed various ways to protect themselves from drugs. When several clinically used photoactive drugs were studied, it was shown that some of them were being actively pumped out by cancer cells, thus likely limiting the full therapeutic potential of these drugs. Blocking cancer cell pumps led to increased accumulation of the drugs inside the cancer cells. These results pave way to further understanding and subsequently addressing cancer resistance mechanisms, potentially leading to improved and prolonged effectiveness of these photoactivated drugs in the future.

Modulight is very happy to be supporting this research. We would like to deliver our warmest congratulations to the research team!

Modulight products used:

ML8500 – Automatic Biomedical Illumination System »

Read more:

In-vitro and in-vivo illumination »

About Modulight’s LASER-SHARP RESEARCH concept:

Laser-Sharp Research is a concept where our scientific board highlights cutting-edge scientific research articles from our customers. Important selection criteria are that Modulight and laser product are mentioned in the publication, the impact and relevance of the results, clinical translatability, as well as scientific quality of the journal. The nominated research groups will be rewarded to encourage the great work done.