The development of modern antibiotics is recognized as one of the major achievements of medicine and has saved millions of lives. However, many infectious agents have developed resistance to antibiotics over time, and defining new antibiotic targets has been difficult since very few genes are essential for pathogens. To combat this growing problem, Professor Timothy Haystead’s team at Duke University developed a novel light-based antimicrobial strategy that targets non-essential enzyme on the surface of bacteria. Light activation was done using ML7710 with 693 nm laser light to generate reactive oxygen species that successfully sterilized the bacteria. The study, published in a renowned journal Cell Chemical Biology, could open possibilities for exploiting larger druggable pool of pathogen targets and mitigate the development of drug resistance.
Modulight is very happy to be supporting this research. We would like to deliver our warmest congratulations to the research team!
#Laser-Sharp Research #Cell #antimicrobial #verteporfin #drugresistance #ML7710
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About Modulight’s LASER-SHARP RESEARCH concept:
Laser-Sharp Research is a concept where our scientific board highlights cutting-edge scientific research articles from our customers. Important selection criteria are that Modulight and laser product are mentioned in the publication, the impact and relevance of the results, clinical translatability, as well as scientific quality of the journal. The nominated research groups will be rewarded to encourage the great work done.
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