Modulight news & articles
Research Articles
Published in: eBioMedicine Authors: Hiroshi Fukushima, Aki Furusawa, Seiichiro Takao, Siddharth S. Matikonda, Makoto Kano, Shuhei Okuyama, Hiroshi Yamamoto, Peter L. Choyke, Martin J. Schnermann, Hisataka Kobayashi A new method called phototruncation-assisted cell tracking (PACT) can be used to noninvasively track migration of immune cells to understand anti-cancer immunity mechanisms. PACT is based on irreversible photo-induced truncation reaction, transforming Cy7 into Cy5 when exposed to NIR light (780 nm). PACT was used in this study to monitor spatiotemporal migration of immune cells between tumor and Continue reading →
Published in: Advanced Science Authors: John A. Quinlan, Collin T. Inglut, Payal Srivastava, Idrisa Rahman, Jillian Stabile, Brandon Gaitan, Carla Arnau Del Valle, Kaylin Baumiller, Anandita Gaur, Wen-An Chiou, Baktiar Karim, Nina Connolly, Robert W. Robey, Graeme F. Woodworth, Michael M. Gottesman, Huang-Chiao Huang University of Maryland Glioblastoma (GBM) is hard to treat due to cellular invasion into functioning brain tissues, limited drug delivery, and evolved treatment resistance. Recurrence is nearly universal even after surgery, chemotherapy, and radiation. Photodynamic therapy (PDT) involves photosensitizer administration followed by light activation to generate reactive oxygen species at tumor sites, thereby killing cells or Continue reading →
Published in: Cell & Bioscience Authors: Aaron Sorrin, Anika Dasgupta, Kathryn McNaughton, Carla Arnau Del Valle, Keri Zhou, Cindy Liu, Dana M. Roque & Huang Chiao Huang Within the last decade, poly(ADP-ribose) polymerase inhibitors (PARPi) have emerged in the clinic as an effective treatment for numerous malignancies. Preclinical data have demonstrated powerful combination effects of PARPi paired with photodynamic therapy (PDT), which involves light-activation of specialized dyes (photosensitizers) to stimulate cancer cell death through reactive oxygen species generation. In this study, a novel combination strategy was Continue reading →
Published in: QUANTUM WEST SPIE 2024 Authors: Kostiantyn Nechay, Luukas Kuusela, Pekko Sipilä, Kalle Palomäki, Petteri Uusimaa Quantum information processing (QIP) approach based on trapped ions is a promising technology that exploits different ion species as individual qubits and qubit gates, while featuring long coherence times, high fidelity of operations, fast readout, and ion-ion gate entanglement. The practical usefulness of trapped-ion quantum computer depends on its further scaling to a large number of qubits. Meanwhile, trapped-ion quantum computer relies on a set of single-frequency lasers, utilizing Continue reading →
Published in: QUANTUM WEST SPIE 2024 Authors: Riina Ulkuniemi, Luukas Kuusela, Mika Mähönen, Timo Aho, Jussi Hämelahti, Andreas Schramm, Soile Talmila, Pekko Sipilä, Petteri Uusimaa Laser systems are utilized in quantum for various applications. Multiple wavelengths and tailored solutions are required depending on the technology that the laser will be applied to. For instance, lasers can be used for controlling particles and molecules, including excitations of the quantum systems. Key performance requirements for lasers used in these applications include narrow linewidth, frequency stability, and single-frequency Continue reading →
Published in: LASE SPIE 2024 Authors: Kostiantyn Nechay, Andreas Schramm, Mika Mähönen, Soile Talmila, Jussi Hämelahti, Pekko Sipilä, Kalle Palomäki, Petteri Uusimaa Quantum information processing based on trapped ion technology is one of the leading platforms, heavily relying on a set of single-frequency lasers in its core operations. Narrow linewidth lasers perform atom photoionization, cooling, state-preparation and read-out. In this work we demonstrate in-house designed and fabricated optically pumped semiconductor laser gain mirror comprised of InGaAs quantum wells and GaAs/AlAs distributed Bragg reflector. We demonstrate Continue reading →
Application notes
Customer case University of Toyama is a Japanese national university located in Toyama City and Takaoka City and established in 1949. It is comprised of 3 former national universities Toyama University, Toyama Medical and Pharmaceutical University, and Takaoka National College. Naoya Ishibashi Daisuke Uta Modulight products: ML6600 Laser use: Studying pain treatment with photobiomodulation. Links to articles: Background Photobiomodulation with low-level laser or light therapy is an effective treatment for pain. It has various effects, such as analgesic (pain-relieving) effects, anti-inflammatory effects, tissue regeneration Continue reading →
Customer case Pharmaceutical Nanotechnology led by Professor Timo Laaksonen on controlled drug release and delivery using modern methods and materials. Particular interest lies in using light to both monitor nanomaterial behavior and to trigger e.g. drug release processes. Modulight products: ML8500, ML6600, MLAKIT Prof. Timo Laaksonen Dr. Tatu Lajunen Laser use: Light-triggered drug release studies from light-activated liposomes. ML8500 with 808 nm wavelength was used to induce the release of calcein from liposomes under different temperatures. The effect of different type of lipids on liposomal Continue reading →
Deadliest cancer Lung cancer is the leading cause of cancer deaths worldwide, with more than 2.2 million cases and 1.8 million deaths each year [1]. Lung cancer can be divided into two types, small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), with the latter accounting for about 85% of all lung cancer cases. NSCL is usually less sensitive to chemo- and radiotherapy and in many cases tumor cannot be removed surgically or has spread from lungs to distant sites at the time Continue reading →
Introduction to DRB lasers Distributed Bragg Reflector (DBR) laser diodes are a class of single-frequency monolithic semiconductor lasers. Monolithic semiconductor lasers in general are small in size, mechanically robust, and have good power conversion efficiency. They also provide opportunities for hybrid integration with photonic integrated circuits (PICs). This application note provides an overview of DBR lasers, their principles of operation, their modal behavior, and their diverse applications. Principles of DBR Laser Operation A DBR laser is a semiconductor laser with one or several quantum wells Continue reading →
Customer case Faculty of Pharmacy at University of Helsinki is specialized in top-level pharmaceutical research. Multidisciplinary research fields include clinical pharmacy, experimental drugs, nanomedicines, and pharmaceutical drug design. Drug delivery unit led by Professor Arto Urtti focuses on design and testing of advanced drug delivery systems especially for ocular indications. Light is studied as an important tool to control the drug delivery to the target tissues. Modulight products: ML6600 (810 nm) + Modulight in vitro illumination kit (MLAKIT) Professor Arto Urtti Senior Pharmaceutical Researcher Tatu Continue reading →
Introduction to fluorescence imaging Fluorescence is a phenomenon where substance that has absorbed certain wavelength of light emits it back at another wavelength. These substances are called fluorophores or fluorescent dyes. The emitted light has a longer wavelength than the absorbed one since some energy of the photon is lost in the process. The difference in wavelengths between absorbed and emitted light, called Stokes shift, allows very low background for fluorescence detection by separating it from the excitation light. The process of fluorescence generation is Continue reading →
Laser-Sharp Research
Modulight Spotlights: LASER-SHARP RESEARCH – March 2024 Glioblastoma is the most aggressive type of brain tumor. It is hard to treat because of its invasion into functioning brain tissues, limited drug delivery due to blood-brain-barrier, and evolved treatment resistance. To address these challenges, a light-activated nanoformulation, called nanoVP, was developed for glioblastoma in a new study co-led by John Quinlan and Collin Inglut in Dr. Huang’s team at the University of Maryland. Published in a prestigious journal Advanced Science, this novel therapy resulted in an improved tumor control and survival Continue reading →
Modulight Spotlights: LASER-SHARP RESEARCH – February 2024 Photoactivated chemotherapy (PACT) is a novel anticancer therapy where cytotoxic drug is attached into a photocage, which is cleaved by light to release the drug at the tumor site. A new study led by Prof. Sylvestre Bonnet’s group at Leiden University, demonstrated a significantly improved agent for photoactivated chemotherapy. ML6600 laser was used to study the drug release from the photocage, comparing efficacy between red and green light. It was shown that the agent could be effectively released Continue reading →
Modulight Spotlights: LASER-SHARP RESEARCH – January 2024 Phototherapy is widely established treatment for skin diseases like actinic keratosis, cutaneous infections, and skin tumors, resulting in excellent cosmetic outcomes. However, some clinically used light sensitizing drugs have drawbacks such as limited penetration depth and high painfulness to patient. In a new study by Andreea Burloiu and the teams at Carol Davila University of Medicine and Pharmacy, new photoactivated drugs were developed for treatment of skin diseases. ML6600 laser with MLAKIT was used to evaluate the effect Continue reading →
Modulight Spotlights: LASER-SHARP RESEARCH – December 2023 Organic compounds are one of the leading causes of water pollution. Rhodamine 6G is a commonly used dye in the food and textile industries and can cause cancer when consumed in contaminated water. To tackle this problem, Professor T. Nyokong’s team at Rhodes University studied photocatalysis with ML7710 for degrading rhodamine, and showed increased degradation efficiency when photocatalysis was combined with ultrasound (sonocatalysis). This Laser-Sharp study offers a new method for more efficient degradation of organic pollutants for environmental Continue reading →
Modulight Spotlights: LASER-SHARP RESEARCH – November 2023 The development of modern antibiotics is recognized as one of the major achievements of medicine and has saved millions of lives. However, many infectious agents have developed resistance to antibiotics over time, and defining new antibiotic targets has been difficult since very few genes are essential for pathogens. To combat this growing problem, Professor Timothy Haystead’s team at Duke University developed a novel light-based antimicrobial strategy that targets non-essential enzyme on the surface of bacteria. Light activation was Continue reading →
Modulight Spotlights: LASER-SHARP RESEARCH – October 2023 Antimicrobial resistance is an increasing healthcare problem, with new effective treatment strategies urgently needed. Professor Mitsunaga and team at The Jikei University Medical School, Japan, describe a promising treatment called photoimmuno-antimicrobial strategy (PIAS) in a new Nature publication. Detailed instructions how to design and implement the treatment are given, with Modulight’s ML7710 and ML6600 series lasers validated for drug activation in the protocol. This treatment enables targeted elimination of different microbes, regardless of the species or drug resistance Continue reading →
Press releases
Modulight achieved the international ISO 27001 information security standard certification today on February 28, 2024. The certification of the information security management system demonstrates the organization's commitment to protecting information and managing high-level of information security. "We are expanding the use of cloud services in accordance with our SaaS business model and are making strong progress in transitioning to a pay-per-treatment (PPT) payment model. Managing patient information requires very high-level information security processes, which is why we started to pursue the ISO 27001 certification in Continue reading →
Modulight is pleased to announce its participation in the GlioLighT project, aimed at developing new treatment options for gliomas. This project has received substantial funding of approximately EUR 2.2 million over three years from the European Innovation Council's Pathfinder program. The GlioLighT project partners include Johannes Gutenberg University Mainz, Aston University in Birmingham, the University of Barcelona, LMU Munich, and MODUS Research and Innovation Ltd. The budgetary allotment of the project for Modulight is about EUR 400,000 over the duration of the project. Gliomas, known Continue reading →
Modulight Forges Strategic Partnership with Laser 2000 UK for Market Expansion in the UK and Ireland
Modulight is pleased to announce a sales partnership with Laser 2000 UK Ltd, a renowned reseller of laser-based solutions in the UK and Ireland. The partnership marks a significant step in expanding Modulight's presence in the UK and Irish markets, leveraging Laser 2000 UK's established customer base, broad sales team, and technical expertise. Under this collaboration, Laser 2000 UK will integrate Modulight's cutting-edge laser technologies into their diverse range of photonics solutions. This synergy is expected to enrich Laser 2000 UK's system solutions offering, particularly Continue reading →
Next week at Photonics West 2024, Modulight will unveil significant new additions to the ML6600 laser solution platform. These new innovations include a specialized laser engine tailored for Flow Cytometry applications, and advanced DBR laser cores designed specifically for the Quantum Computing market. Our #LaserFamily are presenting 11 conference papers plus participating in a technical panel, across the Photonics West conferences BIOS, OPTO, LASE and QUANTUM WEST. You can see the list here. ML6600 for Flow Cytometry – Laser engine with active beam steering The newest product utilizing the ML6600 platform is a specialized laser engine for the Continue reading →
A study published in Science Advances has for the first time scientifically demonstrated the potential of fluorescence-guided photoimmunotherapy enabled with Modulight's laser platform and cloud technology. The study, a collaboration between the University of Maryland (UMD) and Modulight, confirms the benefits of targeted nanomedicine, Modulight’s medical laser system, and fluorescence-guided intervention in both achieving better treatment outcomes and predicting tumor response. "We have already published over a hundred scientific articles on our website from world-leading research groups that have used Modulight products in their studies. This Continue reading →
During this week, Tampere Hall will be filled with experts and scientists in photodynamic therapy as the international congress organized by Modulight gets underway. The biennial congress, the scientific content of which are carefully screened by the International Photodynamic Association (IPA), will give medical researchers, and doctors the opportunity to share their ideas, research results and new discoveries in the field of medicine and technology. The congress, which starts on Monday 10 July, will be opened by Anna-Kaisa Ikonen, Minister of Local Government of Finland, Continue reading →
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Press releases archive
26 Feb 2021 Modulight releasing new 9xx nm diode laser platforms for pumping applications »
18 Mar 2020 Information regarding COVID-19 »
12 Sep 2019 Seppo Orsila nominated as CEO of Modulight »
04 Dec 2018 Modulight becomes exclusive supplier for BAUSCH + LOMB »
03 Apr 2017 Jyrki Liljeroos appointed as Senior Advisor for Modulight Board »
16 Feb 2016 Modulight releases a biomedical illumination system »
16 Sep 2015 Rising star in immunotherapy competition »
28 Jan 2015 Modulight launches the world’s first multi indication CE and ETL certified medical laser »
09 Sep 2014 Modulight ML7710-PDT laser platform CB testing completed »
30 Jan 2014 Modulight broadens their OEM laser system family to single-mode and multi-wavelength laser modules »
14 Nov 2013Modulight launches a product family for photodynamic therapy »
29 Aug 2013Modulight launches a turnkey OEM laser system platform to photodynamic therapy »
20 Jun 2013Kalle Palomaki nominated to Modulight Board »
01 Nov 2012Medical Design Briefs: Therapeutic Laser Systems Improve Quality of Life and Save in Healthcare »
15 Nov 2011Modulight expands LimeLight product family with blue wavelength »
06 Oct 2011Modulight receives ISO 13485:2003 certification for medical laser manufacturing »
19 May 2011Modulight releases multi-chip red laser modules for industrial, display and medical applications »
20 Jan 2011LimeLight laser systems on display in Photonics West at booth #4635 »
13 Jan 2011Modulight adds features and scales up power from FiberLight product platform »
11 Nov 2010Modulight releases OEM laser systems for medical and industrial applications »
16 Sep 2010Modulight releases high-power single-mode lasers at 1310-1650nm for OTDR »
25 Aug 2010Modulight celebrates 10 years anniversary with 35% growth in business »
26 May 2010Modulight welcomes summer by releasing a series of colourful and powerful mounted single-emitters »
30 Apr 2010Modulight appoints new partners in Italy and Singapore »
10 Dec 2009Modulight turning Christmas all red, by adding new red lasers to ChiliLase product »
21 Oct 2009Modulight lasers launched to space on ESA’s SMOS satellite mission »
06 Oct 2009Modulight appoints distribution partner in the United Kingdon and Republic of Ireland »
14 May 2009Modulight celebrates spring by releasing a series of colourful Butterfly lasers »
26 Jan 2009Modulight “FiberLight”, the platform for fiber-coupled high-power lasers from 635 nm to 1550 nm »
14 Nov 2008Modulight introduces “SparkLight”, the turnkey platform for high-power lasers »
06 Nov 2008Modulight scales up power to 20 W at 1470 nm »
04 Sep 2008A new generation of high-power collimated laser modules shines from Modulight »
28 Aug 2008Modulight introduces 1470 nm high-power lasers »
19 Jun 2008Modulight introduces 830 nm high-power lasers »
29 May 2008Modulight to continue supply agreement with Vaisala for meteorological applications »
08 May 2008Modulight to develop high-brightness pump laser technology for European Space Agency »
06 Mar 2008Modulight’s RangerLase provides up to 20 W laser power at 1550 nm »
01 Nov 2007Modulight introduces high-power TO-can red lasers »
17 Oct 2007Modulight introduces high-power 1550nm TO-can lasers »
11 Jun 2007Modulight introduces high-power red laser diodes »
07 Nov 2006Modulight receives 2006 Frost & Sullivan award for Product Innovation »
18 Aug 2006Mr. Orsila continues as chairman and leaves operational role at Modulight »
04 May 2006Modulight develops lasers for the upgrade of European satellite navigation mission Galileo »
31 Jan 2006Modulight awarded a $1.8M contract for high-power laser diodes »
18 Oct 2005Modulight appoints senior advisory board »
07 Mar 2005Tyco Electronics laser unit engages Modulight for design services of laser diode chips »
17 Feb 2005Modulight opens new office to Bay Area »
18 Jun 2004Modulight to deliver world’s first telecommunication laser diodes for space application »
31 May 2004Modulight announces exclusive supply agreement with Vaisala for meteorological applications »
18 May 2004Modulight announces two analog fiber pigtailed laser diodes for CATV »
26 Mar 2004Modulight improves customer service in California, Arizona and near by regions »
22 Jan 2004Modulight enters Israeli market in cooperation with Migvan »
31 Oct 2003Modulight launches uncooled 1310 nm DFB laser »
25 Sep 2003Modulight joins Finnish Ministerial delegation to Japan between 6th and 8th of October »
02 Jul 2003Modulight gets ISO14001 certification »
19 Jun 2003Modulight enhances customer service in China through distribution agreement with Broadtechs »
10 Jan 2003Modulight introduces 10 Gb/s Fabry-Pérot laser »
02 Dec 2002Modulight strengthens its position in Japan »
Nov 2002Compound Semiconductor cover story: “New integrated manufacturing system boosts fab productivity” »
17 Sep 2002Modulight awarded a government contract to develop next generation components »
06 Sep 2002Modulight joins XFP Multi Source Agreement Group »
08 Jul 2002Modulight and Jinsan Scientific into marketing partnership »
03 May 2002Modulight and Mi-Net into marketing partnership »
Newsletters archive
Dec 2018 (3/2018)Modulight becomes exclusive supplier for BAUSCH + LOMB »
Beneath the surface: a day in the life of a laser engineer – mass production of high-end devices»
Jun 2018 (2/2018)Modulight 18 years in business »
Medical device production, prototyping, clinical trials and life cycle management »
Reliable long term supplier with proven production and quality system »
Jan 2018 (1/2018)Business continues to be booming – meet us in San Francisco »
In-vitro laser applications – researcher’s tools »
May 2016 (2/2016)Exciting events ahead – Happy Mothers’ Day »
Rising Star Contest – announcing winner at BMLA »
ASP Conference and Finnish workshop for Pulmonary tests and procedures »
Feb 2016 (1/2016)New year starts with Photonics West and… »
Better life for cancer patients »
Sep 2015 (5/2015)Rising star competition »
Illumination kit for biomedical applications »
Jul 2015 (4/2015)Have a great summer – wishes biomedical laser teenager »
Chosen by yet another pharma »
Plug and play: ML6000 series »
Greetings from Munich, Germany – LASER 2015 »
Mar 2015 (3/2015)Followed by stellar success – ML7710 speaks your language »
Photodynamic therapy: oncologic horizons »
Feb 2015 (1/2015)Meet Modulight team at Photonics West 2015 »
ML7710 – medical laser system update »
On display at PW 2015: ML7710 »
Nov 2014 (3/2014)Meet Modulight team at Medica »
ML7710 – medical laser system update »
Laser modules with compact design and great usability »
White laser – red, green and blue in one package »
Recent highlights in the field of photonics »
Oct 2014 Invitation for Day of Photonics event “Valon Päivä” (in Finnish) »
Oct 2014 (2/2014) Modulight ML7710-PDT medical laser platform receives CB certification »
The Foster Research Group in URMC selected ML7710-PDT for their clinical study programs »
Jan 2014 (1/2014) Modulight medical lasers on display in BIOS (booth #8311) »
Nov 2012 (2/2012)Modulight medical lasers »
Product highlights »
Jan 2012 (1/2012)Product highlights: BIOS and Photonics West »
Dec 2011 (3/2011)Christmas greetings »
Nov 2011 (2/2011)Modulight ISO 13485:2003 certified solutions for medical applications »
May 2011 (1/2011)Modulight products on display in LASER Munich show »
Dec 2010 (3/2010)Latest product introductions »
10 years concluded with record revenue »
Sep 2010 (2/2010)Modulight celebrates 10 years of cool lasers »
May 2010 (1/2010)2010 starting brighter for laser companies »
Dec 2009 (2/2009)Latest product introductions: OEM laser solutions »
ChiliLase products family: red lasers for medical and industrial applications »
Jun 2009 (1/2009)Latest product introductions: 14-pin butterfly series with wavelengths from 630 nm to 1650 nm »
Business case: Modulight’s highly integrated cost-efficient solution for medical device platform »
Dec 2008 (4/2008)Latest product introductions from Modulight: SparkLight, RangerLase family, LumiLase family, High power colimated laser modules »
Oct 2008 (3/2008)Modulight awarded for the second time by Frost & Sullivan »
Latest product introductions: 1470 nm high-power lasers, 830 nm single-mode high-power lasers »
Modulight lasers for medical applications »
Jun 2008 (2/2008)Upcoming products: 3 W turnkey laser system at 635 nm »
Mar 2008 (1/2008)Modulight lasers for pointing and illumination »
Dec 2007 (3/2007)Ready2Lase – Application development program: Paper cutting application »
Oct 2007 (2/2007)Ready2Lase – Application development program: Photodynamic therapy application, Road weather monitoring application »
New product introduction: high-power 1550nm TO-can »
Who are we? Meet Modulight Customer Interaction team »
Jun 2007 (1/2007)Modulight introduces ChiliLase product family »